Registration Dossier

Administrative data

Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
Justification for type of information:
Modelled data on bioaccumulation is being provided to support the PBT assessment.

Data source

Reference
Reference Type:
other: Modelled data
Title:
EPISUITE Results for the Components of CH 302
Author:
U.S. EPA
Bibliographic source:
U.S EPA EPISUITE Model
Report date:
2018

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Modelled data using an acceptable model
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Didodecyl nonylphenyl phosphite
EC Number:
252-457-2
EC Name:
Didodecyl nonylphenyl phosphite
Cas Number:
35239-35-1
Molecular formula:
C39-H73-O3-P
IUPAC Name:
Phosphorous acid, didodecyl nonylphenyl ester
Constituent 2
Chemical structure
Reference substance name:
Dodecyl bis(4-nonylphenyl) phosphite
EC Number:
284-117-4
EC Name:
Dodecyl bis(4-nonylphenyl) phosphite
Cas Number:
84787-76-8
Molecular formula:
C42-H71-O3-P
IUPAC Name:
Phosphorous acid, dodecyl bis(4-nonylphenyl) ester
Constituent 3
Chemical structure
Reference substance name:
4-nonylphenyl ditridecyl phosphite
EC Number:
284-119-5
EC Name:
4-nonylphenyl ditridecyl phosphite
Cas Number:
84787-77-9
Molecular formula:
C41-H77-O3-P
IUPAC Name:
Phosphorous acid, 4-nonylphenyl ditridecyl ester
Constituent 4
Chemical structure
Reference substance name:
Bis(4-nonylphenyl) tridecyl phosphite
EC Number:
284-120-0
EC Name:
Bis(4-nonylphenyl) tridecyl phosphite
Cas Number:
84787-78-0
Molecular formula:
C43-H73-O3-P
IUPAC Name:
Phosphorous acid, bis(4-nonylphenyl) tridecyl ester
impurity 1
Reference substance name:
Tris(nonylphenyl) phosphite
EC Number:
247-759-6
EC Name:
Tris(nonylphenyl) phosphite
Cas Number:
26523-78-4
IUPAC Name:
tris(2-nonylphenyl) phosphite
impurity 2
Reference substance name:
Didodecyl phosphonate
EC Number:
244-325-8
EC Name:
Didodecyl phosphonate
Cas Number:
21302-09-0
Molecular formula:
C24H51O3P
IUPAC Name:
Di(n-dodecyl)hydrogen phosphate
impurity 3
Chemical structure
Reference substance name:
Phenol, 4-nonyl-, branched
EC Number:
284-325-5
EC Name:
Phenol, 4-nonyl-, branched
Cas Number:
84852-15-3
Molecular formula:
C15H24O
IUPAC Name:
4-Nonylphenol, branched
Test material form:
liquid
Specific details on test material used for the study:
Modelled data on the 4 main components of CH 302
Radiolabelling:
no

Results and discussion

Bioaccumulation factor
Temp.:
25 °C
pH:
7
Type:
BCF
Value:
0.9 L/kg
Basis:
not specified
Remarks on result:
not measured/tested
Remarks:
modelled data

Any other information on results incl. tables

The results of the EPISUITE, BCFBAF v3.01 model, for the 4 main components of CH 302 were all approximately 0.9 L/kg ww.

Applicant's summary and conclusion

Conclusions:
The results of the EPISUITE, BCFBAF v3.01 model, for the 4 main components of CH 302 were all approximately 0.9 L/kg ww. Indicating that these substances have a very low potential for bioaccumulation.
Executive summary:

The results of the EPISUITE, BCFBAF v3.01 model, for the 4 main components of CH 302 were all approximately 0.9 L/kg ww. Indicating that these substances have a very low potential for bioaccumulation.