Registration Dossier
Registration Dossier
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EC number: 203-697-1 | CAS number: 109-70-6
Endpoint summary
Administrative data
Description of key information
The following key studies containing 2 study reports have been selected to determinate the skin, eye and respiratory irritation of 1-bromo-3-chloropropane :
- skin irritation to the rabbit (Liggett M.P.)
- eye irritation to the rabbit (Liggett M.P.)
- Characteristics of the General Toxic, Gonadatropic, and Mutagenic Effects of 1,3-chlorobromopropane
- Primary Dermal Irritation Compound TMCB (Ethyl Corporation, unpublished data)
- Characteristics of the General Toxic, Gonadatropic, and Mutagenic Effects of 1,3-chlorobromopropane (Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv)
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
Justification for classification or non-classification
Under the experimental conditions, 1-bromo-3-chloropropane does require labelling with the hazard statement H335 "May cause respiratory irritation" in accordance with the CLP regulation.
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