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Physical & Chemical properties

Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
09 October 2017 to 08 November 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EPA OPPTS 830.7570 (Partition Coefficient, n-octanol / H2O, Estimation by Liquid Chromatography)
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
Qualifier:
according to
Guideline:
other: EC Guideline A.24. Partition Coefficient (n-octanol/water), High Performance Liquid Chromatography (HPLC) Method.
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Specific details on test material used for the study:
Lot number: 2000850599
Analytical method:
other: UPLC
Key result
Type:
Pow
Partition coefficient:
> 16 000 000
Temp.:
35 °C
pH:
ca. 7
Key result
Type:
log Pow
Partition coefficient:
> 7.2
Temp.:
35 °C
pH:
ca. 7
Conclusions:
The HPLC method at neutral pH was applied for the determination of the partition coefficient (Pow) of Tri-o-tolylphosphine.
The Pow and log Pow values of the test item at neutral pH was:

Pow log Pow
Test item > 1.6E7 > 7.2

Description of key information

The HPLC method at neutral pH was applied for the determination of the partition coefficient (Pow) of Tri-o-tolylphosphine.

The Pow and log Pow values of the test item at neutral pH was:

                   Pow             log Pow

Test item       > 1.6E7       > 7.2

Key value for chemical safety assessment

Log Kow (Log Pow):
7.2

Additional information