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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
May 29, 2017 to May 31, 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
European Community (EC), EC No. 761/2009, Part A: Methods for the Determination of Physico-Chemical Properties, Guideline A.4: “Vapour Pressure”, Official Journal of the European Union No. L220, August 24, 2009
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
Organisation for Economic Co-operation and Development (OECD), OECD Guidelines for the Testing of Chemicals No. 104: “Vapour Pressure”, March 23, 2006
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: isothermal thermogravimetry
Specific details on test material used for the study:
No further details specified in the study report.
Key result
Temp.:
20 °C
Vapour pressure:
0.001 Pa
Remarks on result:
other: This value however is expected to be overestimated, because it was deter-mined from the molten material.

Weight loss of the test item in the temperature range of 120 °C to 170 °C

Temperature

[°C]

1/T [K]

1000/T [K]

Weight loss

[μg/min]

VT

[g/cm2h]

Log VT

120

120

120

0.00254

0.00254

0.00254

2.54453

2.54453

2.54453

8.678

11.380

7.166

n.d.

130

130

130

0.00248

0.00248

0.00248

2.48139

2.48139

2.48139

9.4941

1.140

8.709

140

140

140

0.00242

0.00242

0.00242

2.42131

2.42131

2.42131

15.680

15.500

14.450

0.001882

0.001860

0.001734

-2.725473

-2.730487

-2.760951

150

150

150

0.00236

0.00236

0.00236

2.36407

2.36407

2.36407

24.590

25.410

24.600

0.002951

0.003049

0.002952

-2.530060

-2.515814

-2.529884

160

160

160

0.00231

0.00231

0.00231

2.30947

2.30947

2.30947

44.980

44.830

43.800

0.005398

0.005380

0.005256

-2.267799

-2.269250

-2.279345

170

170

170

0.00226

0.00226

0.00226

2.25734

2.25734

2.25734

75.770

78.800

76.470

0.009092

0.009456

0.009176

-2.041321

-2.024293

-2.037328

Estimation of VTand PT:

Log VT/at 20 °C

Log PT/at 20 °C

PT/at 20 °C

-7.0442420

-3.2152005

0.0006093

 

PT[Pa]/at 20 °c

6.09E-04

n.d. – not determined, the weight loss was not reproducible

 

Values of log VT and log PT of the reference items

Reference items

PT20 °C

Literature/Pa

VT20 °C

Extrapolation

Water

Naphthalene

Hexachlorobenzene

Chrysene

2.34E+03

6.50E+00

1.45E-03

8.40E-07

3.64E-02

4.56E-04

4.07E-07

1.59E-10

 

Conclusions:
The isothermal thermogravimetric effusion method was applied for the determination of the vapour pressure of 6,6´-di-tert-butyl-2,2`-thiodi-p-cresol.
A value of the vapour pressure of the test item was determined using the data obtained between 140 °C and 170 °C. The vapour pressure of the test item was calculated (mean of three determinations) to: 6.09E-4 Pa at 20 °C.
This value however is expected to be overestimated, because it was determined from the molten material.
Executive summary:

The purpose of the study was to determine the vapour pressure of the 6,6´-di-tert-butyl-2,2`-thiodi-p-cresol using the isothermal thermogravimetric effusion method. The evaporation rates of the test item at elevated temperatures and ambient pressure were determined by monitoring the weight loss over the time.

 

The isothermal thermogravimetric effusion method was applied for the determination of the vapour pressure of 6,6´-di-tert-butyl-2,2`-thiodi-p-cresol.

 

A value of the vapour pressure of the test item was determined using the data obtained between 140 °C and 170 °C. The vapour pressure of the test item was calculated (mean of three determinations) to: 6.09 × 10-4Pa at 20 °C.

 

This value however is expected to be overestimated, because it was determined from the molten material.

Description of key information

The vapour pressure of the test item was calculated (mean of three determinations) to: 6.09 × 10-4 Pa at 20 °C.

Key value for chemical safety assessment

Vapour pressure:
0.001 Pa
at the temperature of:
20 °C

Additional information

The isothermal thermogravimetric effusion method was applied for the determination of the vapour pressure of 6,6´-di-tert-butyl-2,2`-thiodi-p-cresol.

 

A value of the vapour pressure of the test item was determined using the data obtained between 140 °C and 170 °C. The vapour pressure of the test item was calculated (mean of three determinations) to: 6.09 × 10-4Pa at 20 °C.

 

This value however is expected to be overestimated, because it was determined from the molten material.