Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
1,10-dichlorodecane
EC Number:
218-489-6
EC Name:
1,10-dichlorodecane
Cas Number:
2162-98-3
Molecular formula:
C10H20Cl2
IUPAC Name:
1,10-dichlorodecane
Test material form:
liquid

Study design

Analytical method:
other: Capillary Gas Liquid Chromatography (GLC) Determination

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
4.51
Temp.:
20 °C
Remarks on result:
other: no pH was measured

Any other information on results incl. tables

Vessel #

Phase

Volume Ratio N-octanol:Water

Dil.

Factor

Area Count

Pow

Log Pow

Avg.

Log

Pow

SD

1

Water

1:1

0.05

2.12

23478.3

4.37

4.51

0.2

2.14

Octanol

201

12.43

12.45

2

Water

1:1

0.05

2.11

23621.1

4.37

2.08

Octanol

201

12.32

12.3

3

Water

2:1

0.05

1.82

27107.2

4.43

1.80

Octanol

201

12.16

12.25

4

Water

2:1

0.05

1.81

26972.2

4.43

1.77

Octanol

201

12.09

11.93

5

Water

1:2

0.05

0.93

54466.6

4.74

0.91

Octanol

201

12.42

12.51

6

Water

1:2

0.05

0.92

54707.0

4.74

0.92

Octanol

201

12.68

12.36

Applicant's summary and conclusion

Conclusions:
The partition coefficent of 1, 10 Dichlorodecane (CAS: 2162-98-3) were determined:
Partition Coefficient (log Pow): 4.51
Executive summary:

The partition coefficent of 1, 10 Dichlorodecane (CAS: 2162-98-3) were determined:

Partition Coefficient (log Pow): 4.51