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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 2016-02-18 to 2016-07-18
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
Deviations:
no
GLP compliance:
yes
Type of method:
Laser scattering/diffraction
Type of distribution:
volumetric distribution
Key result
Percentile:
D10
Mean:
10.23 µm
St. dev.:
0.15
Key result
Percentile:
D50
Mean:
80.31 µm
St. dev.:
1.04
Key result
Percentile:
D90
Mean:
387.45 µm
St. dev.:
16.97

The particle size distribution was determined in an experimental study under GLP conditions according to OECD Test Guideline 110 using the laser diffraction method.

The median mass diameter was determined as 80.31 µm, while the 10% quantile was 10.23 µm and the 90%-quantile was 387.54 µm.

This corresponded with the following fractions:

up to 2 µm: 0.8%

2 -200 µm: 76.1%

> 200 µm: 23.1%

All %-values are the average of two measurements.

Conclusions:
The median particle diameter was determined as 80.31 µm, while the 10%-quantile was 10.23 µm and the 90%-quantile was 387.54 µm.
Executive summary:

The particle size distribution was determined in an experimental study under GLP conditions according to OECD Test Guideline 110 using the laser diffraction method with dry dispersion.

The median particle diameter was determined as 80.31 µm, while the 10%-quantile was 10.23 µm and the 90%-quantile was 387.54 µm.

Description of key information

The median particle diameter was determined as 80.31 µm, while the 10 %-quantile was 10.23 µm and the 90 %-quantile was 387.54 µm (reference 4.5-1).

Additional information

The particle size distribution was determined in an experimental study under GLP conditions according to OECD Test Guideline 110 using the laser diffraction method with dry dispersion.

The median particle diameter was determined as 80.31 µm, while the 10 %-quantile was 10.23 µm and the 90 %-quantile was 387.54 µm.