Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Short term aquatic toxicity

Fish

Key Study:

In an OECD 203 study, according to GLP, the 96 hour toxicity (LC50) of exposure of fathead minnow (Pimephales promelas) to the test item resulted in an LC50 value of greater than 100% v/v saturated solution, based on the nominal test concentration. The No Observed Effect Concentration (NOEC) was 100% v/v saturated solution (Envigo Research Limited, Ltd, 2018).

 

Invertebrates

Key Study:

In an OECD 202 study, conducted according to GLP, the acute toxicity of the test item to the freshwater invertebrate Daphnia magna was investigated and based on the geometric mean measured test concentrations gave a 48-Hour EC50 value of greater than 0.0076 mg/L as zinc (equivalent to 0.071 mg/L as test item).  The No Observed Effect Concentration was 0.0076 mg/L as zinc (equivalent to 0.071 mg/L as test item) mg/L.  This study showed that there were no toxic effects at saturation (Envigo Research Limited, Ltd, 2018).

 

Algae

Key Study:

In an OECD 201 study, conducted according to GLP, the effect of the test item on the growth of Pseudokirchneriella subcapitata was investigated and the 72 hour EC50 value based on growth rate was determined to be greater than 100% v/v saturated solution, the NOEC was given as 12.5% v/v saturated solution and the LOEC determined to be 25% v/v saturated solution (Envigo Research Limited, Ltd, 2018).

 

Micro-organisms

Key Study:

In an OECD 209 study, conducted according to GLP, No effects of the test item were observed on the respiration of activated sewage sludge following a 3-hour exposure, resulting in an EC50 value of greater than 1000 mg/L.  The No Observed Effect Concentration (NOEC) following the 3-hour exposure was 1000 mg/L (Envigo Research Limited, Ltd, 2018).