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PBT assessment

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PBT assessment: overall result

Reference
Name:
Zinc bis(dipentyldithiocarbamate)
Type of composition:
legal entity composition of the substance
State / form:
liquid
Reference substance:
Composition 1
PBT status:
the substance is not PBT / vPvB
Justification:

Conclusion on P / vP properties: vP (and P)

The test item is not readily biodegradable (21% degradation in 28 days) and is therefore considered to be very Persistant (vP) based upon the information available.

Conclusion on B / vB properties: not B/vB

The water solubility and partition coefficient (Log Pow) of the substance are 0.086 mg/L and > 9.4, respectively.  The typical molecular mass of the substance (C22H44N2S4Zn) is 530.27 daltons.  These data indicate that the substance is relatively large (> 500 daltons), has very low water solubility (< 0.1 mg/L), and is a highly lipophilic (Log Pow > 5.6) molecule, and thus is not expected to be absorbed by fish. In addition, acute oral toxicity study in rats did not show any systemic effects up to 2000 mg/kg, the highest doses tested.  Although the substance was not tolerated after 3 doses at 500 mg/kg/day or 2 doses at 1000 mg/kg/day and the rats were euthanized due to local effects on fore stomach and corresponding poor clinical conditions in the repeated dose oral range-finding toxicity study in rats, the substance did not induce any systemic effects up to 250 mg/kg/day, the highest doses tested in the combined repeated dose oral toxicity study with the reproductive/developmental toxicity screening test in rats.

Conclusion on T properties: not T

No evidence of toxicity has been reported in any study on the test item

Likely routes of exposure:

The primary route of test item release release will be to wastewater.

It may be released to air through use processes, however, the vapour pressure is 6.3 x 10-11Pa

at 25 °C and therefore air exposure is expected to be negligible.

 

Release to soil may occur from spreading of STP sludge’s, however this is advised against.