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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

2,2-bis(hydroxymethyl)propane-1,3-diyl didocosanoate (CAS 68258-72-0) is characterised by a low vapour pressure (VP < 0.001 Pa at 20 °C, SPARC (v4.6)), a low water solubility (3.5 µg/L at 20 °C, pH = 6.3) and a high log Koc indicating a high adsorption potential to soil and sediment particles (log Koc > 5, MCI method, KOCWIN v2.00). Based on the result from biodegradation study according to OECD 301F the substance is not readily biodegradable (25.6-30.2% after 28 d). However, in the case insoluble chemicals enter a standard Sewage Treatment Plant (STP), they will be extensively removed in the primary settling tank and fat trap and thus, only limited amounts will get in contact with activated sludge organisms, according to the Guidance on information requirements and chemical safety assessment, Chapter R.7b (ECHA, 2016). As a result of the high adsorption potential of the substance (log Koc > 5, MCI method, KOCWIN v2.00) a removal from the water column to a significant degree by adsorption to sewage sludge can be expected (Guidance on information requirements and chemical safety assessment, Chapter R.7b, ECHA, 2016). In conclusion, the concentration of the substance in conventional STP effluents is presumably marginal. Abiotic degradation via hydrolysis is considered as not relevant for the substance. Calculations using HYDROWIN v2.00 predict half-lives > 1 year for the constituents of the substance at pH 7 and 212.9 d - 1.2 yr at pH 8 (Müller, 2016). Moreover, the substance is not volatile (VP < 0.001 Pa at 20 °C) and thus evaporation to the air and subsequent transport through the atmosphere to other environmental compartments is not likely. However, if the substance is released into air, the substance is susceptible to indirect photodegradation in air by OH-radicals as half-lives of less than 24 hours were calculated for the main components of the substance (Müller, 2016).

Based on the physico/chemical properties such as low water solubility and high potential for adsorption a reduced availability in water is expected. The high molecular weight of the substance constituents (781.31 - 1426.47 g/mol) significantly reduces the absorption due to steric hindrance to cross biological membranes. It can be concluded that the bioaccumulation potential of 2,2-bis(hydroxymethyl)propane-1,3-diyl didocosanoate is negligible. BCF/BAF values estimated by QSAR (BCFBAF v3.01) also support this assumption (BCF values all well below 2000 L/kg).

Please refer to IUCLID Section 5.3 for a detailed overview on bioaccumulation of the substance.