Registration Dossier
Registration Dossier
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EC number: 479-310-7 | CAS number: -
Endpoint summary
Administrative data
Description of key information
The following Acute toxicity studies are available:
Acute Oral toxicity study (rat)
Acute dermal toxicity study (rabbit)
Acute inhalation toxicity (rats)
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 5 000 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Dose descriptor:
- LC50
- Value:
- 5 000 mg/m³
Acute toxicity: via dermal route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 5 000 mg/kg bw
Additional information
Acute oral (male and female rats), acute dermal (male and female rabbits) and acute inhalation (male and female rats) toxicity studies were performed with Fyrolflex SOL-DP.
Following either oral or dermal administration no mortalities were observed in either sex at 5000 mg/kg, no signs of systemic toxicity were noted during clinical observations and no abnormalities were noted during necropsy.
Following the 4 hours inhalation exposure to 5.23 mg/l aerosol SOL-DP, no exposure related findings were shown in clinical signs of both sexes and only a minor effect on bodyweight profile was noted. Limited necropsy findings were observed in the lungs and mandibular lymph nodes of some animals, and the lung: body weight ratios were considered to be normal.
Justification for classification or non-classification
The above results triggered no classification under the EEC criteria for classification and labelling requirements for Dangerous Substances and Preparations (67/548/EEC) and the CLP Regulation (EC No 1272/2008). Therefore, Fyrolflex SOL-DP is not classified for acute toxicity.
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