Symclosene

Particle size distribution (Granulometry)

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Principles of method if other than guideline:

Particle size analysis was performed as part of a 36 month storage stability study. The determination was carried out initially, and after storage at 25°C for period of 24 and 36 months using a procedure based on Method MT58.2 of the CIPAC Handbook for the Analysis of Technical and Formulated Pesticides.

GLP compliance:

yes

Percentile:

D50

Remarks on result:

other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.

No.:

#1

Size:

ca. 250 µm

Distribution:

5.4 %

No.:

#2

Size:

ca. 125 µm

Distribution:

4.6 %

Table 2: Particle size

	Percentage <250 μm	Percentage <125 μm
Initial:	5.40%	4.60%
24 months	3.51%	3.19%
36 months	4.46%	3.58%

Conclusions:

There was no significant change in the particle size distribution of the test material during storage at 25 ±2°C for 36 months.

Reference 2

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Principles of method if other than guideline:

The particle size distribution of trichloroisocyanuric acid products was determined to define the levels of respirable dust present. The data was developed through a combination of gravimetric analysis and laser diffraction particle size analysis for both granular and tableted products.

GLP compliance:

no

Type of method:

other: combination of gravimetric analysis and laser diffraction particle size analysis

Percentile:

D50

Remarks on result:

other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.

No.:

#1

Size:

10.78 µm

Distribution:

ca. 0.02 %

No.:

#2

Size:

52.63 µm

Distribution:

ca. 0.2 %

Table 1: Findings of the study on trichloroisocyanuric acid products

Sample no	Vibration test	Starting material (g)	Recover,100 mesh		Thru 100 mesh (%)	Transfer losses (%)	Cum < 10.78 micron		Cum < 52.63.micron
			> (g)	< (g)			In < 100 mesh cut (%)	In product (%)	In < 100 mesh cut (%)	In product (%)
3” tablets
3-3A	No	18026	18013	10.41	0.06	0.014	9.70	0.0056	46.27	0.0267
4-3B	No	17806	17791	15.18	0.09	0.002	12.23	0.0104	50.89	0.0434
5-3C	No	17928	17912	14.44	0.08	0.009	12.80	0.0103	52.95	0.0426
3” tablets
2-2A	Yes	18167	18079	85.69	0.47	0.013	11.35	0.0535	50.33	0.2374
6-2B	Yes	18165	18068	126.26	0.69	0.004	12.74	0.0884	54.09	0.3753
8-2C	Yes	18045	18042	2.15	0.01	0.005	12.00	0.0014	52.58	0.0063
1” tablets
1-1A	No	6974	6964	8.66	0.12	0.019	11.51	0.0143	47.86	0.0594
7-1B	No	6879	6862	13.8	0.20	0.047	13.93	0.0279	53.58	0.1075
1” tablets
7A	Yes	18317	18150	161.97	0.88	0.029	11.88	0.1051	48.24	0.4266
7B	Yes	16621	16441	174.11	1.05	0.035	13.02	0.1364	51.09	0.5352
7C	Yes	16586	16444	132.8	0.80	0.055	11.84	0.0948	49.14	0.3935
ACL 90 XG
10A	No	5475	5434	18.25	0.33	0.416	9.86	0.0329	54.37	0.1812
ACL 90 XG
9A	Yes	17978	17934	3.54	0.02	0.225	4.05	0.0008	9.95	0.0020
9B	Yes	18005	17962	7.46	0.04	0.197	6.76	0.0028	29.48	0.0122
9C	Yes	18001	17896	12.11	0.07	0.516	15.25	0.0103	59.55	0.0401
ACL 90 XG							Cum < 10.39 micron		Cum < 53.51.micron
N/A							8.86		42.03

 

Conclusions:

Without vibration – levels of respirable dust for all materials analysed was less than 0.06%, with most samples being less than 0.02% for the 10.78 micron range, and less than 0.2% (typical values of less than 0.05%) for the 52.63 micron range. With vibration – vibration of the granular materials did not appear to make any difference

Description of key information

In a PSD study levels of respirable dust for samples analysed was less than 0.06%, with most samples being less than 0.02%  for the 10.78µm range and less than 0.2% (typical values of less than 0.05%) for the 52.63µm.  As part of the storage stability study the initial measurement of particle size  was determined to be 5.4% particles < 250 µm and 4.6 % particles < 125 µm.

Additional information

The particle size distribution of trichloroisocyanuric acid products was determined to define the levels of respirable dust present (Schwartz & Johnson 1995).

As part of a 36 month storage stability study with ACL 90 XG (trichloroisocyanuric acid) particle size was determined initially, and after storage at 25°C for period of 24 and 36 months (O'Connor & Mullee 2003).