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Administrative data

Endpoint:
appearance / physical state / colour
Type of information:
experimental study
Adequacy of study:
key study
Study period:
11 Dec - 18 Dec 2017
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Basic data given (comparable to guidelines/standards)
Cross-reference
Reason / purpose for cross-reference:
reference to other study
Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
11 Dec - 18 Dec 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
GLP guideline study
Reason / purpose for cross-reference:
reference to other study
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
2008
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
1995
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: ASTM D5972 – Standard Test Method for Freezing Point of Aviation Flues (Automatic Phase Transition Method), ASTM International, West Conshohocken; PA, 2016
Version / remarks:
2016
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
Italian Ministry of Health, Rome, Italy
Type of method:
method to determine freezing temperature
Melting / freezing pt.:
-57.31 °C
Remarks on result:
other: see Remarks
Remarks:
freezing temperature

The freezing temperature of the sample labelled as 2E4MZ-CN is -57.31°C (the mean of two measurements).

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guideline
Qualifier:
no guideline required
Principles of method if other than guideline:
Visual inspection during freezing point measurement.
GLP compliance:
yes (incl. QA statement)
Remarks:
Italian Ministry of Health, Rome, Italy

Test material

Constituent 1
Chemical structure
Reference substance name:
Reaction mass of 2-ethyl-4-methyl-1H-imidazole-1-propiononitrile and 2-ethyl-5-methyl-1H-imidazole-1-propiononitrile
EC Number:
947-727-8
Cas Number:
568591-00-4
Molecular formula:
C9H13N3
IUPAC Name:
Reaction mass of 2-ethyl-4-methyl-1H-imidazole-1-propiononitrile and 2-ethyl-5-methyl-1H-imidazole-1-propiononitrile

Results and discussion

Physical state at 20°C and 1013 hPa:
liquid
Form / colour / odour
Form:
liquid
Colour:
light yellow
Substance type:
organic

Applicant's summary and conclusion