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Physical & Chemical properties

Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Study period:
December 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Qualifier:
no guideline available
Principles of method if other than guideline:
algebric calculation of the log of the ratio of solubility in octanol and solubility in water of target substance, experimentally determinated.
GLP compliance:
no
Type of method:
estimation method (solubility ratio)
Partition coefficient type:
octanol-water
Specific details on test material used for the study:
Ester A is a dense gel
Analytical method:
other: algebric calculation of log solublity ratio
Key result
Type:
log Pow
Partition coefficient:
ca. 4.6
Temp.:
20 °C
pH:
ca. 6.2
Conclusions:
ESTER A logP(ow) is about 4.6
Executive summary:

Ester A logP(ow) was calculated by the ratio of solubilities in water and in octanol, experimentally determined fot the test material at 20°C.

The solubility in octanol using the flask method was performed on the substance and it is 27.1 g/L.

Water solubility of Ester A was evaluated with a preliminary test and a final test. Medium final solubility of Ester A is: 0,63 mg/L at 20 °C and pH 6.2.

Ester A logP(ow) was about 4.6

Description of key information

Key value for chemical safety assessment

Log Kow (Log Pow):
4.6
at the temperature of:
20 °C

Additional information

Ester A logP(ow) was calculated by the ratio of solubilities in water and in octanol, experimentally determined fot the test material at 20°C.

The solubility in octanol using the flask method was performed on the substance and it is 27.1 g/L.

Water solubility of Ester A was evaluated with a preliminary test and a final test. Medium final solubility of Ester A is: 0,63 mg/L at 20 °C and pH 6.2.

Ester A logP(ow) was about 4.6