Registration Dossier

Diss Factsheets

Toxicological information

Sensitisation data (human)

Currently viewing:

Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Basic data given

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1973

Materials and methods

Type of sensitisation studied:
skin
Study type:
study with volunteers
Test guideline
Qualifier:
according to guideline
Guideline:
other: human patch test (Procter & Gamble Company)
GLP compliance:
no

Test material

Constituent 1
Reference substance name:
Automatically generated during migration to IUCLID 6, no data available
IUPAC Name:
Automatically generated during migration to IUCLID 6, no data available
Details on test material:
- Name of test material (as cited in study report): AC-Base (Sodium Aluminosilicate)
- Composition of test material, percentage of components: Na: 13.4%, Al: 15.0%
- 5% aqueous paste: Silicon: 11.5%, Na2O: 12.9%, H2O: 19.0%
- Chemical name: Zeolite, cuboidal, crystalline, synthetic, non-fibrous
- Framework: cuboidal
- Related CAS number. 1318-02-1

Method

Type of population:
not specified
Ethical approval:
not specified
Subjects:
71 subjects
Clinical history:
no data
Controls:
no data
Route of administration:
dermal

Results and discussion

Any other information on results incl. tables

No evidence of sensitization was seen in any subject.
AC-base was very mild under patching conditions.

Applicant's summary and conclusion

Conclusions:
not sensitising

Categories Display