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Environmental fate & pathways

Hydrolysis

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Description of key information

The hydrolysis as function of pH was determined according to OECD-guideline no.111 and Council Regulation (EC) no.440/2008, Method C.7. The preliminary test was conducted under GLP with test item concentration of 50 μg of active ingredient/L in buffer solution at pH 4, 7, 9 at temperature of 50°C.

Key value for chemical safety assessment

Half-life for hydrolysis:
1 yr
at the temperature of:
25 °C

Additional information

Since the test item was found to be stable in the preliminary test (less than 10% of the applied test item was transformed after 120 hrs for pH 4 and 12 days for pH 7 and 9), no further testing was deemed necessary.

Reaction rate constants and half lives could not be calculated due to the fact that the test item undergoes no significant hydrolysis. With regard to the guideline a half-life of > 1 year could be assumed at ambient temperature.