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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1.12.2015 - 31.3.2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report date:
2015

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
yes (incl. QA statement)
Type of method:
column elution method

Test material

Constituent 1
Chemical structure
Reference substance name:
2-(3,5-dichloro-2-hydroxyphenyl)-3,4-dihydroquinazolin-4-one
EC Number:
600-418-9
Cas Number:
1033-16-5
Molecular formula:
C14H8Cl2N2O2
IUPAC Name:
2-(3,5-dichloro-2-hydroxyphenyl)-3,4-dihydroquinazolin-4-one
Test material form:
solid
Details on test material:
Expiration: unlisted
Storage condition of test material: at the room temperature in tightly closed container

Results and discussion

Water solubility
Key result
Water solubility:
0.027 mg/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
ca. 7

Applicant's summary and conclusion

Conclusions:
The determined water solubility of the test substance, 2-(3’,5’-Dichloro-2’-hydroxyphenyl)-4-quinazolinone, was lower than the limit of quantification of used analytical method (LOQ = 0.0094 mg/L).
Test was performed at the temperature of 20°C.