Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 615-086-0 | CAS number: 70225-05-7
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Readily biodegradability data from OECD 301B or 301F testing for a series of closely related trimellitate esters indicate that the submission substance, CAS No. 70225-05-7, would expected to be inherently biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- inherently biodegradable
Additional information
Ready biodegradability studies have been carried out for a series of closely related trimellitate esters including the ester reaction products of branched tridecanol, isodecanol and trimellitic anhydride (CAS No. 70225-05-7). The results indicate that the biodegradability of these materials can vary considerably, ranging from <5% to 46.8% in 28 days and to as much as 60.9% in 39 days. The submission substance was found to biodegrade <2% in a 28 day ready biodegradation test. By comparison, tri-2-ethylhexyl trimellitate (CAS No. 3319-31-1) has been reported to be biodegraded from 3.4 to 46.8% biodegradation in 28 days and as much as 60.9% in 39 days. The exact reasons for the wide variation among study results are unclear, but contributing factors may include low water solubility of the trimellitate esters which could limit their bioavailability or access/contact to microbial enzymes in the aqueous solution carrying out hydrolysis and metabolism/breakdown. Other variables such as degree of agitation/mixing, test material bioavailability/contact with microbial population in the test system, slow initial hydrolysis rate, as well as variation in inoculum and interlaboratory testing. Overall, the trimellitate ester materials were not readily biodegradable (>60% in 28 days). The overall evaluation of the available data suggest that the trimellitate esters are expected to be at least inherently biodegradable under favorable environmental conditions. This appears to be consistent with the recent SIDS evaluation by the US EPA that trimellitate ester HPV chemicals as a general chemical category are sufficiently biodegradable and are not expected to be persistent or bioaccumulative (US EPA 2009).
Based on the above data considerations, trimellitate esters such as ester reaction products of branched tridecanol, isodecanol and trimellitic anhydride (CAS No. 70225-05-7) would be expected to be inherently biodegradable in the standard OECD ready biodegradability test.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
