Registration Dossier

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.8 (Partition Coefficient - HPLC Method)
Deviations:
no
GLP compliance:
yes
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Specific details on test material used for the study:
Identification: 2-ethylhexyl 7-oxabicyclo[4.1.0]heptane-3-carboxylate
Appearance/Physical state: Clear colourless liquid
Batch: AH03201
Purity: 99.47%
Expiry date: 01 February 2019
Storage conditions: Approximately 4 °C, in the dark
Analytical method:
high-performance liquid chromatography
Type:
log Pow
Partition coefficient:
0 - 0
Temp.:
30 °C
pH:
6.2
Conclusions:
The partition coefficient of the test item has been determined to be in the range 1.01 x 105 to 1.37 x 105, log10 Pow in the range 5.0 and 5.1.
Executive summary:

In the range 1.01 x 105 to 1.37 x 105, log10 Pow in the range 5.0 to 5.1, using the HPLC method, designed to be compatible with Method A.8 Partition Coefficient of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 117 of the OECD Guidelines for Testing of Chemicals, 13 April 2004.

Description of key information

Key value for chemical safety assessment

Log Kow (Log Pow):
5.1
at the temperature of:
30 °C

Additional information

The partition coefficient of the test item has been determined to be in the range 1.01 x 105 to 1.37 x 105, log10 Pow in the range 5.0 and 5.1.