Registration Dossier

Physical & Chemical properties

Solubility in organic solvents / fat solubility

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
no data
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Insufficient documentation for an assessment of reliability.
Qualifier:
no guideline followed
Principles of method if other than guideline:
no data
GLP compliance:
not specified
Medium:
methanol
Solubility:
6.45 other: g/100 mL solution
Medium:
ethanol
Solubility:
5.55 other: g/100 mL solution
Medium:
isopropanol
Solubility:
3.88 other: g/100 mL solution
Medium:
other: dichloromethane
Solubility:
> 50 other: g/100 mL solution
Medium:
other: 2-propanone
Solubility:
> 50 other: g/100 mL solution
Medium:
dimethylformamide
Solubility:
> 50 other: g/100 mL solution
Details on results:
no data
Conclusions:
The solubility of T000625 was determined in different organic solvent and ranged from 3.88 g/100 mL in isopropanol to > 50 g/100mL in DCM, DMF or 2-propanone.

Description of key information

A K4 study reports various solubilities of test substance in different organic solvents (J&J PRD), see additional information.

Key value for chemical safety assessment

Additional information

 Solvent

Solubility [g/100mL solution]

 methanol  6.45
 ethanol  5.55
 isopropanol  3.88
 dichloromethane  > 50
 2 -propanone  > 50
 dimethylformamide  > 50