Registration Dossier

Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: The result was obtained from a peer reviewed source.

Data source

Reference
Reference Type:
publication
Title:
The assay of acute vapor toxicity, and the grading and interpretation of results on 96 chemical compounds
Author:
Carpenter CP, Smyth HF Jr, Pozzani UC
Year:
1949
Bibliographic source:
J Ind Hyg Toxicol 31:343-346.

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
Unknown.
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
26-24-2
IUPAC Name:
26-24-2
Constituent 2
Reference substance name:
3-Chloro-1,2-propanediol
IUPAC Name:
3-Chloro-1,2-propanediol

Test animals

Species:
rat

Administration / exposure

Route of administration:
inhalation
Duration of exposure:
4 h

Results and discussion

Effect levels
Sex:
male
Dose descriptor:
LC50
Effect level:
> 0.397 - < 0.786 mg/L air (nominal)

Applicant's summary and conclusion

Interpretation of results:
toxic
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
The substance is toxic by inhalation.