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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: The result was obtained from a peer reviewed source.

Data source

Reference
Reference Type:
publication
Title:
Chemosterilant and rodenticidal effects of 3-chloro-1, 2-propanediol (Epibloc) against the albino laboratory rat and the Nile field rat.
Author:
Helal, T.Y.
Year:
1982
Bibliographic source:
Internat. Pest Control. 24, 20-23.

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
Deatails not evident.
GLP compliance:
not specified
Test type:
other: Details not evident

Test material

Constituent 1
Reference substance name:
3-chloropropane-1,2-diol
EC Number:
202-492-4
EC Name:
3-chloropropane-1,2-diol
Cas Number:
96-24-2
IUPAC Name:
3-chloropropane-1,2-diol
Constituent 2
Reference substance name:
3-Chloro-1,2-propanediol
IUPAC Name:
3-Chloro-1,2-propanediol

Test animals

Species:
rat
Strain:
other: Albino and Nile
Sex:
male

Results and discussion

Effect levelsopen allclose all
Sex:
male
Dose descriptor:
LD50
Effect level:
26 mg/kg bw
Remarks on result:
other: Albino rat
Sex:
male
Dose descriptor:
LD50
Effect level:
58 mg/kg bw
Remarks on result:
other: Nile rat

Applicant's summary and conclusion

Interpretation of results:
toxic
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
The substance is toxic by ingestion.