Registration Dossier

Administrative data

Endpoint:
vapour pressure
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the melting point is above 300°C
other:
Justification for type of information:
From assessment based on molecular weight, melting point and structural analysis (modelling with EPISuite), the vapour pressure is considered minimal.
The substance is supplied in water and it is not possible to remove the water (vapour pressure of water is about 3.1 kPa at 25 C)
The vapour pressure of the triethanolamine is about 2 Pa at 25 C and due to water solubility, will partition into water (Low H)
Cross-reference
Reason / purpose:
data waiving: supporting information
Reference
Endpoint:
appearance / physical state / colour
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Justification for type of information:
Company report on attempts to remove water
Qualifier:
no guideline followed
Principles of method if other than guideline:
FT-IR performed on a sample, before and after rotary evaporation of water, to investigate whether the identity of the MK310K remains unchanged on drying
GLP compliance:
no
Specific details on test material used for the study:
Sample Ref 91602-001; starting at ca 40% in water
Physical state at 20°C and 1013 hPa:
liquid
Form:
liquid: viscous
Colour:
Amber
Odour:
ammonia-like
Substance type:
organic

The water-free material produced was a gel-like consistency, but in the form manufactured and supplied, it is a mobile liquid in water.

Conclusions:
Not possible to remove water without decomposition. Report attached (using IR to demonstrate chemical changes on drying)
Supplied as a mobile solution in water.

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion