Phenol, paraalkylation products with C10-15 branched olefins (C12 rich) derived from propene oligomerization, carbonates, calcium salts, sulfurized, including distillates (petroleum), hydrotreated, solvent-refined, solvent-dewaxed, or catalytic dewaxed, light or heavy paraffinic C15-C50

Bioaccumulation: aquatic / sediment

Description of key information

A weight of evidence is presented to demonstrate the lack of bioaccumulation potential for this substance. A BCF of 2.2 is assigned for risk assessment purposes and, while this value was obtained using an alternative method instead of, e.g., a standard OECD 305 fish bioconcentration study, this value is reasonable according to a weight of evidence approach. 

Key value for chemical safety assessment

BCF (aquatic species):

2.2 dimensionless

Additional information

Key study:

The key study (Rausina et al., 1996) is considered to have a reliability of 2 according to the criteria of Klimisch, 1997 as the study was well-conducted but a non-guideline and non-GLP study.

This test system utilizes Semipermeable Membrane Devices (SPMDs), first developed by the United States Fish and Wildlife Service for field sampling studies assessing environmental contamination. SPMDs are low-density polyethylene tubing, with a pore-size similar to the cell membranes in fish. SPMDs are filled with the lipid triolein, the predominant lipid in fishes, and function as "model fish or mollusks" with selective membranes and lipid reservoirs that concentrate organic compounds from water. The BCF of EC 701-251-5 was determined to be 2.2 in this study.

 

Supporting study 1:

BCF was modelled using LMC OASIS Catalogic BCF base-line (v.02.09) modeling software, including multiple representative structures of this UVCB. The predicted BCF was 7.76, which is consistent with the low BCF obtained from the SPMD study.

 

Supporting study 2:

A Klimisch code 1 OECD 305 and GLP study was conducted with TPP (EC 310-154-3), which is present in the registered substance as a residual impurity/constituent. The steady state BCF value assigned is 823. Steady-state TPP concentrations were achieved in the tissues of rainbow trout (Oncorhynchus mykiss) after 3 days for both the 1.1 and 11 μg/L treatment groups. Steady-state BCF values based on total radioactivity TPP concentrations were 289, 1601 and 823 in edible, nonedible and whole fish tissue, respectively, for the 1.1 μg/L treatment group, and 289, 1428 and 749 in edible, nonedible and whole fish tissue, respectively, for the 11 μg/L treatment group. TPP was eliminated quickly with mean tissue concentrations 10% or less than the mean measured steady-state test concentrations by Day 11.