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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

The EC50 is the value from the OECD Guideline 201 72-hour Selenastrum capricornutum assay conducted in accordance with GLP by Weytjens and Wils (1991) on 3-methylpyridine.  This EC50 was the key value for short-term toxicity to aquatic algae for all chemicals in the category (i.e., pyridine, 2-methylpyridine, 3-methylpyridine and 4-methylpyridine).

Key value for chemical safety assessment

EC50 for freshwater algae:
320 mg/L

Additional information

The point of departure for the derivation of the PNECaquaticwas the EC50 value from the 72-hour Selenastrum capricornutum (aquatic alga) assay and the EC50 value from the 48-hour Daphnia magna (aquatic invertebrate) conducted by Weytjens and Wils (1991) on 3-methylpyridine; these two EC50 values (which were equivalent) represented the lowest of the short-term toxicity values for each of three trophic levels (fish, aquatic invertebrates and aquatic algae), and were selected as the point of departure for the derivation of the PNECaquatic for the chemical category including pyridine, 2-methylpyridine, 3-methylpyridine and 4-methylpyridine.