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PBT assessment

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PBT assessment: overall result

Reference
Name:
Gamma Picoline
Type of composition:
legal entity composition of the substance
State / form:
liquid
Reference substance:
Gamma Picoline
PBT status:
the substance is not PBT / vPvB
Justification:

Type of Data

PBT-Criterion

vPvB-Criterion

Value for Substance

Conclusion

Persistence

 

 

 

 

Ready Biodegradability test

Not readily

Not readily

Readily biodegradable

Not P, not vP

Inherent Biodegradability

t1/2> 60 days in marine water, or

 

 

 

 

t1/2> 40 days in fresh or estuarine water, or

t1/2> 60 days in marine, fresh- or estuarine water, or

 

 

 

t1/2> 180 days in marine sediment, or

t1/2> 180 days in marine, fresh- or estuarine sediment, or

 

 

 

t1/2> 120 days in soil

t1/2> 180 days in soil

 

 

Abiotic degradation

 

 

 

 

Photodegradation

 

 

 

 

Bioaccumulation

 

 

 

 

Evidence of biomagnification

BCF > 2000 L/kg

BCF > 5000 L/kg

Predicted BCF =2.965 L/kg

Not B, not vB

Octanol-water partition coefficient (screening)

Log Kow≥ 4.5

Log Kow≥ 4.5

Log Kow= 1.22

Not B, not vB

Toxicity

 

 

 

 

 

NOEC (long-term) < 0.01 mg/L, or

 

Short term LC50 > 100 mg/L

Not T

 

Classification as carcinogenic (category 1A or B) , germ cell mutagenic (category 1 or 1B) or toxic for reproduction (category 1A, 1B or 2) according to the CLP Regulation, or

 

Not CMR

Not T

 

Evidence of chronic toxicity and classification as specific target organ toxicity after repeated exposure (STOT RE category 1 or 2) according to the CLP Regulation.

 

No evidence of chronic toxicity

Not T

 

 

 

 

 

Detailed information regarding the PBT/vPvB determination is summarised in the table (above). The substance has been shown to be readily biodegradable and therefore is not persistent. The substance has an octanol-water partition coefficient (log Kow) of 1.22, substantially below the screening criterion of 4.5, above which a substance may be considered bioaccumulative and very bioaccumulative; the substance has a predicted BCF of 2.965 L/kg, substantially below both the definitive BCF thresholds of 2000 L/kg for bioaccumulative and 5000 L/kg for very bioaccumulative. This substance does not meet the screening criteria for aquatic toxicity, as the lowest short-term L(E)C50value of 320 mg/L is substantially above the definitive criterion of L(E)C50< 0.01 mg/L and the screening criterion of L(E)C50< 0.1 mg/L for aquatic toxicity. The substance does not meet any of the criteria for mammalian toxicity in accordance with the CLP Regulation, i.e., carcinogenic (category 1A or 1B), mutagenic (category 1 or 1B), toxic for reproduction (category 1A, 1B or 2), or other evidence of chronic toxicity, i.e., specific target organ toxicity after repeated exposure (STOT RE category 1 or 2). Thus, the substance has been determined to be not persistent, not bioaccumulative and not toxic, and is considered to be not PBT and not vPvB.