Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-626-4 | CAS number: 108-89-4
Categories
- Category name:
- Pyridine and Pyridine Derivatives
Justifications and discussions
- Category definition:
- The category of pyridine and methyl-pyridine derivatives is established based on structural similarity and similar properties including toxicological behaviour.
- Category description:
- Pyridine is the sentinel substance, with the methyl derivatives as members with no specific order.
- Category rationale:
- A category of pyridine and alkyl pyridine derivatives is comprised of: pyridine (CASRN 110-86-1), 2-picoline (CASRN 109-06-8), 3-picoline (CASRN 108-99-6), and 4-picoline (CASRN 108-89-4). The basis of the category is structural similarity (based on the pyridine unsaturated ring structure) and similar physical properties, environmental fate and toxicity, and mammalian toxicity. Similar toxicological properties derive from common pathways of metabolism and elimination among all members of the category. The U.S. Environmental Protection Agency has accepted this category, as indicated in its September 2009 Hazard Characterization Document reviewing the screening-level data set submitted by an industry consortium under the voluntary High Production Volume (HPV) Challenge Program.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
