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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Experimental Starting Date: 21 July 2015 Experimental Completion Date: 22 July 2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results. The study report was conclusive, done to a valid guideline and the study was conducted under GLP conditions.
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
GLP compliance:
yes
Type of method:
effusion method: vapour pressure balance
Key result
Temp.:
25 °C
Vapour pressure:
0.297 Pa
Transition / decomposition:
no

Results

Recorded temperatures, mass differences and the resulting calculated values of vapour pressure are shown in the following tables:

 

Run 1

 

Table 3.1– Vapor Pressure Data

 

Temperature (ºC)

Temperature (K)

Reciprocal Temperature (K-1)

Mass Difference (µg)

Mass Difference (kg)

Vapor Pressure (Pa)

Log10Vp

23

296.15

0.003376667

164.03

1.640E-07

0.227715664

-0.642607094

24

297.15

0.003365304

185.86

1.859E-07

0.258021297

-0.588344446

25

298.15

0.003354016

209.34

2.093E-07

0.290617553

-0.536678159

26

299.15

0.003342805

240.91

2.409E-07

0.334444801

-0.475675551

27

300.15

0.003331667

257.00

2.570E-07

0.356781843

-0.447597255

28

301.15

0.003320604

297.32

2.973E-07

0.412756333

-0.384306255

29

302.15

0.003309614

317.54

3.175E-07

0.440826873

-0.355731938

30

303.15

0.003298697

371.51

3.715E-07

0.515751060

-0.287559870

31

304.15

0.003287851

370.97

3.710E-07

0.515001402

-0.288191589

32

305.15

0.003277077

416.70

4.167E-07

0.578486358

-0.237706878

33

306.15

0.003266373

483.27

4.833E-07

0.670902573

-0.173340542

 

A plot of Log10(vapor pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 1 gives the following statistical data using an unweighted least squares treatment.

 

Slope:

-4.09 x 103

Standard error in slope:

128

Intercept:

13.2

Standard error in intercept:

0.425

 

The results obtained indicate the following vapor pressure relationship:

 

Log10(Vp (Pa)) = -4.09 x 103/temp(K) + 13.2.

 

The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -0.537.

Run 2

 

Table 3.2– Vapor Pressure Data

 

Temperature (ºC)

Temperature (K)

Reciprocal Temperature (K-1)

Mass Difference (µg)

Mass Difference (kg)

Vapor Pressure (Pa)

Log10Vp

23

296.15

0.003376667

137.93

1.379E-07

0.191482177

-0.717871643

24

297.15

0.003365304

182.36

1.824E-07

0.253162400

-0.596600795

25

298.15

0.003354016

205.80

2.058E-07

0.285703126

-0.544085008

26

299.15

0.003342805

240.97

2.410E-07

0.334528096

-0.475567401

27

300.15

0.003331667

262.30

2.623E-07

0.364139601

-0.438732088

28

301.15

0.003320604

302.37

3.024E-07

0.419767027

-0.376991679

29

302.15

0.003309614

349.33

3.493E-07

0.484959538

-0.314294495

30

303.15

0.003298697

417.26

4.173E-07

0.579263781

-0.237123625

31

304.15

0.003287851

457.86

4.579E-07

0.635626983

-0.196797675

32

305.15

0.003277077

522.82

5.228E-07

0.725808106

-0.139178186

33

306.15

0.003266373

604.45

6.045E-07

0.839131459

-0.076169997

 

A plot of Log10(vapor pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 2 gives the following statistical data using an unweighted least squares treatment.

 

Slope:

-5.51 x 103

Standard error in slope:

149

Intercept:

17.9

Standard error in intercept:

0.496

 

The results obtained indicate the following vapor pressure relationship:

 

Log10(Vp (Pa)) = -5.51 x 103/temp(K) + 17.9.

 

The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -0.556.

Run 3

 

Table 3.3– Vapor Pressure Data

 

Temperature (ºC)

Temperature (K)

Reciprocal Temperature (K-1)

Mass Difference (µg)

Mass Difference (kg)

Vapor Pressure (Pa)

Log10Vp

23

296.15

0.003376667

190.90

1.909E-07

0.265018108

-0.576724450

24

297.15

0.003365304

221.80

2.218E-07

0.307915225

-0.511568837

25

298.15

0.003354016

242.36

2.424E-07

0.336457772

-0.473069435

26

299.15

0.003342805

269.87

2.699E-07

0.374648700

-0.426375770

27

300.15

0.003331667

301.25

3.013E-07

0.418212180

-0.378603323

28

301.15

0.003320604

347.26

3.473E-07

0.482085848

-0.316875618

29

302.15

0.003309614

377.43

3.774E-07

0.523969537

-0.280693962

30

303.15

0.003298697

421.78

4.218E-07

0.585538699

-0.232444396

31

304.15

0.003287851

474.25

4.743E-07

0.658380502

-0.181523039

32

305.15

0.003277077

534.86

5.349E-07

0.742522710

-0.129290259

33

306.15

0.003266373

600.98

6.010E-07

0.834314210

-0.078670359

 

A plot of Log10(vapor pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 3 gives the following statistical data using an unweighted least squares treatment.

 

Slope:

-4.43 x 103

Standard error in slope:

51.7

Intercept:

14.4

Standard error in intercept:

0.172

 

The results obtained indicate the following vapor pressure relationship:

 

Log10(Vp (Pa)) = -4.43 x 103/temp(K) + 14.4.

 

The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -0.473.

Run 4

 

Table 3.4– Vapor Pressure Data

 

Temperature (ºC)

Temperature (K)

Reciprocal Temperature (K-1)

Mass Difference (µg)

Mass Difference (kg)

Vapor Pressure (Pa)

Log10Vp

23

296.15

0.003376667

171.31

1.713E-07

0.237822169

-0.623747664

24

297.15

0.003365304

173.30

1.733E-07

0.240584799

-0.618731816

25

298.15

0.003354016

207.08

2.071E-07

0.287480094

-0.541392222

26

299.15

0.003342805

226.75

2.268E-07

0.314787093

-0.501983083

27

300.15

0.003331667

266.90

2.669E-07

0.370525579

-0.431181805

28

301.15

0.003320604

292.32

2.923E-07

0.405815052

-0.391671849

29

302.15

0.003309614

338.33

3.383E-07

0.469688720

-0.328189870

30

303.15

0.003298697

366.90

3.669E-07

0.509351199

-0.292982667

31

304.15

0.003287851

432.72

4.327E-07

0.600726222

-0.221323410

32

305.15

0.003277077

478.56

4.786E-07

0.664363886

-0.177593983

33

306.15

0.003266373

528.82

5.288E-07

0.734137643

-0.134222507

 

A plot of Log10(vapor pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 4 gives the following statistical data using an unweighted least squares treatment.

 

Slope:

-4.69 x 103

Standard error in slope:

118

Intercept:

15.2

Standard error in intercept:

0.391

 

The results obtained indicate the following vapor pressure relationship:

 

Log10(Vp (Pa)) = -4.69 x 103/temp(K) + 15.2.

 

The above yields a vapor pressure (Pa) at 298.15 K with a common logarithm of -0.543.

Conclusions:
The vapor pressure of the test item has been determined to be 0.297 Pa at 25 ºC.
Executive summary:

The determination was carried out using a procedure designed to be compatible with Method A4 Vapour Pressure of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 104 of the OECD Guidelines for Testing of Chemicals, 23 March 2006.

 

Instrument:                                               Vapor pressure balance.

Summary of Results

The values of vapor pressure at 25 °C extrapolated from each graph are summarized in the following table:

 

Table 3.5 – Summary of Vapor Pressure Data

 

Run

Log10[Vp(25 ºC)]

1

-0.537

2

-0.556

3

-0.473

4

-0.543

Mean

-0.527

Vapor Pressure

0.297 Pa

 

The test item did not change in appearance under the conditions used in the determination.

Conclusion

The vapor pressure of the test item has been determined to be 0.297 Pa at 25 ºC.

 

Description of key information

The vapour pressure of the substance has been determined to be 0.297 Pa at 25 ºC.

Key value for chemical safety assessment

Vapour pressure:
0.297 Pa
at the temperature of:
25 °C

Additional information