Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
The study was conducted between 27 April 2018 and 18 May 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
Date of Inspection: 18/07/2017 - 20/07/2017 Date of Issue: 28/11/2017
Type of method:
differential scanning calorimetry

Test material

Constituent 1
Chemical structure
Reference substance name:
trans-cinnamic acid
EC Number:
205-398-1
EC Name:
trans-cinnamic acid
Cas Number:
140-10-3
Molecular formula:
C9H8O2
IUPAC Name:
3-phenylacrylic acid
Test material form:
solid: particulate/powder
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 20171106
- Expiration date of the lot/batch: 10 April 2020

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: Room temperature, in the dark, over silica gel

Results and discussion

Melting / freezing point
Key result
Melting / freezing pt.:
133.4 °C

Any other information on results incl. tables

Thermal Event

Interpretation

Temperature (°C)

Determination 1

Determination 2

Endotherm

Onset of boiling

133.51

133.19

Determination 1: 133.51 °C

Determination 2: 133.19 °C

Mean melting temperature: 133.4 ± 0.5 °C (406.5 ± 0.5 K)

Applicant's summary and conclusion

Conclusions:
The melting point of the test item has been determined to be 133.4 ± 0.5 °C (406.5 ± 0.5 K).
Executive summary:

The melting point is determined to be 133.4 ± 0.5 °C (406.5 ± 0.5 K), by differential scanning calorimetry, designed to be compatible with Method A.1 Melting/Freezing Temperature of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 102 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.