Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Reference
Reference Type:
publication
Title:
Yakugaku Zasshi
Author:
Yakugaku Zasshi
Year:
1961
Bibliographic source:
Yakugaku Zasshi. Journal of Pharmacy. Vol. 81, Pg. 1225

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
No further information available
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Pyruvic acid
EC Number:
204-824-3
EC Name:
Pyruvic acid
Cas Number:
127-17-3
Molecular formula:
C3H4O3
IUPAC Name:
2-oxopropanoic acid
Test material form:
liquid

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
subcutaneous
Vehicle:
not specified
Control animals:
not specified

Results and discussion

Effect levels
Key result
Sex:
not specified
Dose descriptor:
LC50
Effect level:
ca. 3 533 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion