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Ecotoxicological information

Endpoint summary

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Description of key information

HMDTMP sodium salt will fully dissociate in aqueous solution and will behave no differently to the parent HMDTMP acid and its sodium counter ions at equivalent concentrations. It is not expected that the counter ion will contribute significantly to the overall toxicity of HMDTMP(4 -7Na). Therefore, the impact on aquatic organisms will be dominated by the effects of the HMDTMP acid.

Short-term marine toxicity data are available with the registered substance for fish and invertebrates. A 96 h L(E)C50 value between >1000 and <3000 mg active acid/L and of 1000 mg active acid/L have been determined with Cyprinodon variegatus and Paleomonetes pugio respectively.

Short-term freshwater toxicity data are available with the structural analogue HMDTMP acid (EC 245-781-0, CAS 23605-74-5) for fish, invertebrates and algae:
Fish: 96-hour LC50 440 mg active acid/L, Oncorhynchus mykiss

Invertebrates: 48-hour EC50 570 mg active acid/L, Daphnia magna

Algae: 96-hour EC50 28 mg active acid/L and 96-hour NOEC 10 mg active acid/L (calculated by reviewer), Scenedesmus subspicatus (new name: Pseudokirchneriella subcapitata)

A long-term toxicity to invertebrate study has been read across from a structurally similar substance, ATMP acid (EC 229-146-5, CAS 6419-19-8). A 28-day EC50 of  ≥ 25 mg active acid/L was calculated for the effects of ATMP acid on the adult survival of Daphnia magna.

A long-term toxicity to fish study has been read-across from a structurally similar substance, ATMP acid (EC 229-146-5, CAS 6419-19-8).

A 60-day NOEC of 23 mg active acid/L was calculated for the effects of ATMP acid on the length and weight of Oncorhynchus mykiss fry.

A toxicity to microorganisms (ASRI) study has been read-across from a structurally similar substance, EDTMP sodium salt (EC 244-742-5, CAS 22036-77-7). A 3-hour EC50 of > 100mg active acid/L was calculated for the effects of EDTMP sodium salt on the inhibition of respiration of waste-water treatment plant microorganisms.

Additional information