Registration Dossier

Administrative data

Endpoint:
surface tension
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2009-03-25 - 2009-08-20
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP Guideline Study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2009
Report Date:
2009

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 115 (Surface Tension of Aqueous Solutions)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.5 (Surface Tension)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
ring method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): LCA08042
- Substance type: white and beige solid
- Physical state: solid
- Analytical purity: 99.4%
- Lot/batch No.: 0826000002
- Expiration date of the lot/batch: September 16, 2001
- Storage condition of test material: At room temperature (about 20°C)

Results and discussion

Surface tension
Surface tension:
50.2 mN/m
Temp.:
20.3 °C
Conc.:
0.1 vol%

Any other information on results incl. tables

Table 1: Determination of the Calibration factor using water

Time expired [h:min]

Temperature [°C]

Surface tension

Calibration factor (F)

measured

Mean(sg)

00:32

19.8

70.7

70.30

1.0353

00:33

19.8

70.2

00:34

19.8

70.2

00:35

19.8

70.2

00:36

19.8

70.2

00:37

19.8

70.3

 

With         so= 72.78 mN/m at 20.0°C

                 F=so/sg

                 F= 72.78 / 70.30 = 1.0353

 

Where     F= Calibration factor

                 so= Surface tension of water at the test temperature

                 sg= Measured value of the surface tension of water at the test temperature

 

 

Table 2: Determination of the surface tension for the test item solution

Time expired [h:min]

Temperature [°C]

Surface tension measured

[mN/m]

Mean value (s*)

Mean corrected for calibration (s1)

Mean corrected for Harkins-Jordan (s)

First sample

00:34

20.2

50.1

49.78

51.54

50.22

00:35

20.2

49.8

00:36

20.2

49.7

00:37

20.2

49.7

00:38

20.2

49.7

00:39

20.2

49.7

Second sample

00:31

20.3

49.9

49.73

51.49

50.16

00:32

20.3

49.7

00:33

20.3

49.7

00:34

20.3

49.7

00:35

20.3

49.7

00:36

20.3

49.7

 

Mean value from both samples:s= 50.2 mN/m

 

With s*×F=s1                                F= Calibration factor = 1.0353

and s1×Fc=s                                  Fc= Correction factor acc. to Harkins

                        = 0.974 for 51.54 mN/m and 0.974 for 51.49 mN/m

 

 

Applicant's summary and conclusion

Conclusions:
The surface tension of LCA08042 in water (at a concentration of about 0.1%) was determined to be 50.2 mN/m at 20.3 °C ± 0.1 °C.
Based on the criteria as outlined in the EEC Guideline, LCA08042 is a surface active substance.
Executive summary:

The determination of the surface tension of an aqueous solution of LCA08042 was based on the OECD Guideline No. 115: “Surface Tension of Aqueous Solutions” (1995) and on the EEC Directive 92/69, EEC Publication No. L383, December 1992 and the Council Regulation (EC) No. 440/2008, 30 May 2008, Part A, Methods for the determination of physico-chemical properties, A.5 “Surface tension”.

The surface tension of LCA08042 in water (at a concentration of about 0.1%) was determined to be 50.2 mN/m at 20.3 °C ± 0.1 °C. Based on the criteria as outlined in the EEC Guideline, LCA08042 is a surface active substance.