Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 200-607-2 | CAS number: 65-31-6
Manufacture, use & exposure
Formulation
Documentsopen allclose all
Formulation
- Registration/ Notification status for the use:
- use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
Contributing activity / technique for the environment
- Environmental release category (ERC):
- ERC2: Formulation into mixture
Contributing activity / technique for workersopen allclose all
- Name of activity / technique:
- Fume hoods are used when possible. Packaging and transfers of larger quantities of the substance and mixtures are done under open system conditions within a controlled secluded area. Mixing is done under closed batch conditions, but mixing systems are in some cases temporarily opened during mixing for sampling purposes.
- Process category (PROC):
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- PROC 4: Chemical production where opportunity for exposure arises
- PROC 5: Mixing or blending in batch processes
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
- Name of activity / technique:
- Granulation is important in mixture processing.
- Process category (PROC):
- PROC 14: Tabletting, compression, extrusion, pelletisation, granulation
- Name of activity / technique:
- Cleaning of industrial equipment is always done manually before repairs and occasional maintenance.
- Process category (PROC):
- PROC28: Manual maintenance (cleaning and repair) of machinery
- Product category formulated:
- PC 0: Other: Use in nicotine bitartrate dihydrate containing mixtures
- Substance supplied to that use in form of:
- as such
- Related assessment:
- use assessed in an own CSR
Formulation
- Registration/ Notification status for the use:
- use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
Contributing activity / technique for the environmentopen allclose all
- Name of activity / technique:
- Formulation into mixture
- Environmental release category (ERC):
- ERC2: Formulation into mixture
- Name of activity / technique:
- Formulation into solid matrix
- Environmental release category (ERC):
- ERC3: Formulation into solid matrix
Contributing activity / technique for workersopen allclose all
- Name of activity / technique:
- Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions - solid 100%
- Process category (PROC):
- PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions - liquid 2%
- Process category (PROC):
- PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions - solid 2%
- Process category (PROC):
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions - liquid 2%
- Process category (PROC):
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment condition - solid 2%
- Process category (PROC):
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment condition - liquid 2%
- Process category (PROC):
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Chemical production where opportunity for exposure arises - solid 2%
- Process category (PROC):
- PROC 4: Chemical production where opportunity for exposure arises
- Name of activity / technique:
- Chemical production where opportunity for exposure arises - liquid 2%
- Process category (PROC):
- PROC 4: Chemical production where opportunity for exposure arises
- Name of activity / technique:
- Mixing or blending in batch processes - solid 2%
- Process category (PROC):
- PROC 5: Mixing or blending in batch processes
- Name of activity / technique:
- Mixing or blending in batch processes - liquid 2%
- Process category (PROC):
- PROC 5: Mixing or blending in batch processes
- Name of activity / technique:
- Transfer of substance or mixture (charging and discharging) at non-dedicated facilities - solid 100%
- Process category (PROC):
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- Name of activity / technique:
- Transfer of substance or mixture (charging and discharging) at non-dedicated facilities - solid 2%
- Process category (PROC):
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- Name of activity / technique:
- Transfer of substance or mixture (charging and discharging) at non-dedicated facilities - liquid 2%
- Process category (PROC):
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- Name of activity / technique:
- Transfer of substance or mixture (charging and discharging) at dedicated facilities - solid 100%
- Process category (PROC):
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Name of activity / technique:
- Transfer of substance or mixture (charging and discharging) at dedicated facilities - solid 2%
- Process category (PROC):
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Name of activity / technique:
- Transfer of substance or mixture (charging and discharging) at dedicated facilities - liquid 2%
- Process category (PROC):
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Name of activity / technique:
- Transfer of substance or mixture into small containers (dedicated filling line, including weighing) - solid 100%
- Process category (PROC):
- PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
- Name of activity / technique:
- Transfer of substance or mixture into small containers (dedicated filling line, including weighing) - solid 2%
- Process category (PROC):
- PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
- Name of activity / technique:
- Transfer of substance or mixture into small containers (dedicated filling line, including weighing) - liquid 2%
- Process category (PROC):
- PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
- Name of activity / technique:
- Use as laboratory reagent - solid 100%
- Process category (PROC):
- PROC 15: Use as laboratory reagent
- Name of activity / technique:
- Use as laboratory reagent - liquid 2%
- Process category (PROC):
- PROC 15: Use as laboratory reagent
- Name of activity / technique:
- Manual maintenance (cleaning and repair) of machinery - solid 100%
- Process category (PROC):
- PROC28: Manual maintenance (cleaning and repair) of machinery
- Name of activity / technique:
- Manual maintenance (cleaning and repair) of machinery - liquid 2%
- Process category (PROC):
- PROC28: Manual maintenance (cleaning and repair) of machinery
- Product category formulated:
- PC 0: Other: nicotine containing products
- Related assessment:
- use assessed in an own CSR
Formulation
- Registration/ Notification status for the use:
- use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
Contributing activity / technique for the environment
- Environmental release category (ERC):
- ERC2: Formulation into mixture
Contributing activity / technique for workersopen allclose all
- Name of activity / technique:
- Fume hoods are used when possible. Packaging and transfers of larger quantities of the substance and mixtures are done under open system conditions within a controlled secluded area. Mixing is done under closed batch conditions, but mixing systems are in some cases temporarily opened during mixing for sampling purposes.
- Process category (PROC):
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- PROC 4: Chemical production where opportunity for exposure arises
- PROC 5: Mixing or blending in batch processes
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
- Name of activity / technique:
- Granulation is important in mixture processing.
- Process category (PROC):
- PROC 14: Tabletting, compression, extrusion, pelletisation, granulation
- Name of activity / technique:
- Cleaning of industrial equipment is always done manually before repairs and occasional maintenance.
- Process category (PROC):
- PROC28: Manual maintenance (cleaning and repair) of machinery
- Product category formulated:
- PC 0: Other: Use in nicotine bitartrate dihydrate containing mixtures
- Substance supplied to that use in form of:
- as such
- Related assessment:
- use assessed in an own CSR
- Insignificant exposure via the following route:
- oral
- Pattern of exposure:
- occasional
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
