Registration Dossier
Registration Dossier
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EC number: 216-652-6 | CAS number: 1634-02-2
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 952
- Report date:
- 1952
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 401 (Acute Oral Toxicity)
- GLP compliance:
- not specified
- Test type:
- standard acute method
- Limit test:
- no
Test material
- Reference substance name:
- Tetrabutylthioperoxydicarbamic acid
- EC Number:
- 216-652-6
- EC Name:
- Tetrabutylthioperoxydicarbamic acid
- Cas Number:
- 1634-02-2
- Molecular formula:
- C18H36N2S4
- IUPAC Name:
- tetrabutylthioperoxydicarbamic acid
- Test material form:
- liquid
Constituent 1
Test animals
- Species:
- mouse
- Sex:
- not specified
Administration / exposure
- Route of administration:
- other: Intraperitoneal
- Vehicle:
- not specified
Results and discussion
Effect levels
- Dose descriptor:
- LD50
- Effect level:
- >= 2 350 mg/kg bw
Applicant's summary and conclusion
- Interpretation of results:
- Category 5 based on GHS criteria
- Conclusions:
- TBUT has shown intraperitoneal LD50 as >2350mg/kg bw.
- Executive summary:
Intraperitoneal route of administration is seen as a very worse case scenario for toxicity testing. There is anecdotal evidence that the lethal dosage for oral administration is considered double compared to intraperitoneal administration. Therefore, the overall conclusion is that the substance can be considered for classification as non-hazardous for acute oral toxicity.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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