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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
September 14, 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
EU Regulation (EC) 440/2008, Annex Part A
Deviations:
no
GLP compliance:
yes
Type of method:
isoteniscope
Test no.:
#1
Temp.:
20 °C
Vapour pressure:
< 100 Pa
Test no.:
#2
Temp.:
20 °C
Vapour pressure:
< 100 Pa
Test no.:
#3
Temp.:
20 °C
Vapour pressure:
< 100 Pa
Key result
Temp.:
20 °C
Vapour pressure:
< 100 Pa
Remarks on result:
other: Mean

Test Results

Test Number

Deionised Water*

(Pa)

PPG-2 Myristyl Ether Propionate (Pa)

1

2320 < 100

2

2333 < 100

3

2333 < 100

Average

2329 < 100

*Deionised water used as a reference.

Conclusions:
The vapour pressure of PPG-2 myristyl ether propionate was observed to be <100 Pa at 20 °C.
Executive summary:

An experiment was carried out for PPG-2 myristyl ether propionate to establish an endpoint value for vapour pressure in line with OECD Guideline 104 (Vapour Pressure Curve) and Method A.4 (Vapour Pressure) from EU Regulation (EC) 440/2008, Annex Part A. The isoteniscope technique, based on the principle of the static method, was utilised. The experiment was performed in triplicate and an average of <100 Pa at 20 °C determined for the vapour pressure of PPG-2 myristyl ether propionate.

Description of key information

A study was performed to determine the vapour pressure of PPG-2 myristyl ether propionate. Using the isoteniscope technique, a final value of < 100 Pa at 20 °C was calculated as the mean of three replicates. 

Key value for chemical safety assessment

Vapour pressure:
100 Pa
at the temperature of:
20 °C

Additional information

The final value recommended for chemical safety assessment has been obtained from a key study undertaken according to OECD Guideline 104 (Vapour Pressure Curve) and Method A.4 (Vapour Pressure) from EU Regulation (EC) 440/2008 (Annex Part A) without deviation. The endpoint value has subsequently been assigned a Klimisch score of 1 (reliable without restriction).

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