Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 232-601-0 | CAS number: 9001-37-0
Endpoint summary
Administrative data
Description of key information
The short-term toxicity to aquatic invertebrates and to aquatic algae and cynobacteria of the present target substance, Glucose oxidase IUBMB 1.1.3.4, has not been determined but another enzyme (Peroxidase, IUBMB 1.11.1.7) has been analyzed and used as a source substance for read-across.
Peroxidase was tested on aquatic invertebrate Daphnia magna and algae Scenedesmus subspicatus.
Analysis of the immobility of Daphnia magna exposed to peroxidase to concentrations up to 546.6 mg enzyme concentrate dry matter/L for 48 hours gave an EC50 value of 92.7 mg enzyme concentrate dry matter/L, equivalent to 26.2 mg/L active enzyme protein.
Exposure of Scenedesmus subspicatus to peroxidase for 72 hours in concentrations up to 976 mg enzyme concentrate dry matter/L produced the following EC50 and NOEC values:
ErC50 (24 - 72 h): 624.6 mg enzyme concentrate dry matter/L, equivalent to 176.6 mg active enzyme protein/L.
EbC50 (72 h): 312.3 mg enzyme concentrate dry matter/L.
"No observed effect level" for 72 hour AUC: 122 mg enzyme concentrate dry matter/L, equivalent to 34.5 mg active enzyme protein/L.
"No observed effect level" for the 24-72 hour growth rate: 488 mg enzyme concentrate dry matter/L, equivalent to 138 mg active enzyme protein/L.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
