Registration Dossier

Physical & Chemical properties

Water solubility

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Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report Date:
2018

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
About 10 g of test material was mixed in 100 ml water and then it was temperated to 20 OC. After 1 hour, the mixing was stopped and some ml sample was taken through a filter. The sample was placed into the spectrofotometer and the absorbance was measured. from the calibration line, or from the correlation equation the concentra-tion of uric acid can be calculated. (Result: Absorbance: 1,232 Concentration: 1,476 mg/100 ml)
GLP compliance:
no
Type of method:
other: UV-Vis spectrofotometer: Simadzu UV1800
Remarks:
Cuvette: OPTECH S/Q/10 quarz, 10*10 mm

Test material

Reference
Name:
Unnamed
Test material form:
solid: particulate/powder
Details on test material:
It was manufactured by MOLAR CHEMICALS Ltd.

Results and discussion

Water solubility
Key result
Water solubility:
ca. 15.52 mg/L
Conc. based on:
test mat.
Loading of aqueous phase:
100 g/L
Incubation duration:
ca. 1 h
Temp.:
20 °C
pH:
ca. 4.976

Applicant's summary and conclusion

Conclusions:
solubility in water is 15.52 mg/l
Executive summary:

solubility in water is 15.52 mg/l