Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report Date:
2018

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
It was calculated from the measured solubility datas
GLP compliance:
no
Type of method:
estimation method (solubility ratio)
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Test material form:
solid: particulate/powder
Details on test material:
It was manufactured by MOLAR CHEMICALS Ltd.

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
ca. -1.149
Temp.:
20 °C
pH:
ca. 4.976
Details on results:
It was estimated from the measured solubility data.

Partition coefficient (n-octanol/water) log P (o/w)
Result
log P (n-octanol) = log 1,118 = 0,041
log P (water) = log 15,52 = 1,190
log P(o/w) = 0,041-1,190 = - 1,149

Applicant's summary and conclusion

Conclusions:
Partition coefficient (n-octanol/water) log P (o/w) = - 1.49
Executive summary:

Partition coefficient (n-octanol/water) log P (o/w) = - 1.149