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EC number: 229-158-0 | CAS number: 6420-33-3
The substance has a low vapour pressure and during use no exposure to aerosols with droplets in the inhalable or respirable range is expected.
A safety factor of 3 has been used to convert the LOAEL from the oral study to a NOAEL
Route to route extrapolation taking into account that dermal absorption is set at 10%, while oral absorption is set at 50% (in view of the systemic effects on liver and kidney seen in the repeated dose study) leads to the NOAEL of 50 mg/kg bw that is taken as starting point for the calculation of the DNEL.
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