Registration Dossier

Administrative data

First-aid measures

· Description of first aid measures
· General information:
Immediately remove any clothing soiled by the product.
Take note of the following instructions:
· After inhalation:
Supply fresh air. If required, provide artificial respiration. Keep patient warm. Consult doctor if symptoms persist.
In case of unconsciousness place patient stably in the recovery position for transportation.
Call a doctor immediately.
· After skin contact:
Immediately wash with water and soap and rinse thoroughly.
If skin irritation occurs, consult a doctor.
· After eye contact: Rinse opened eye for several minutes under running water. Then consult a doctor.
· After swallowing: Do not induce vomiting; call for medical help immediately.

· Most important symptoms and effects, both acute and delayed
No further relevant information available.

· Indication of any immediate medical attention and special treatment needed
No further relevant information available.

Fire-fighting measures

Extinguishing media
· Suitable extinguishing agents:
CO2, powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
· For safety reasons unsuitable extinguishing agents: Water with full jet

· Special hazards arising from the substance or mixture
Can form explosive gas-air mixtures.
In case of fire, the following can be released:
Carbon monoxide and carbon dioxide
Metal oxide fume

· Advice for firefighters
· Protective equipment:
Mount respiratory protective device.
Do not inhale explosion gases or combustion gases.
Wear personal protective equipment.
· Additional information
Cool endangered container(s) with water spray.
Heating of container(s) will cause pressure rise with risk of bursting and subsequent explosion BLEVE).
Dispose of fire debris and contaminated fire fighting water in accordance with official regulations.

Accidental release measures

Personal precautions, protective equipment and emergency procedures
Wear personal protective equipment. Keep unprotected persons away.

· Environmental precautions:
Inform respective authorities in case of seepage into water course or sewage system.
Do not allow to enter sewers/ surface or ground water.

· Methods and material for containment and cleaning up:
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).
Dispose contaminated material as waste according to specifications.
Ensure adequate ventilation.
Clean the affected area carefully; suitable cleaners are:
Warm water

Handling and storage

· Precautions for safe handling
Ensure good ventilation/exhaustion at the workplace.
Store in cool, dry place in tightly closed receptacles.
Keep away from heat and direct sunlight.
Prevent static electric sparks.
Prevent formation of aerosols.
· Information about fire - and explosion protection:
Keep ignition sources away - Do not smoke.
Protect against electrostatic charges.
Protect from heat.
Traces of flammable substances may collect in the steam chamber of enclosed systems. Keep clear of ignition sources.
Fumes can combine with air to form an explosive mixture.
When heated the product forms flammable fumes.
The product is flammable.
Heating of container(s) will cause pressure rise with risk of bursting and subsequent explosion (BLEVE).
The vapour may be invisible and is heavier than air. It spreads along the ground and may enter sewers and basements.

· Conditions for safe storage, including any incompatibilities
· Storage:
· Requirements to be met by storerooms and receptacles: Store only in the original container.
· Information about storage in one common storage facility:
Do not store together with acids.
Do not store together with oxidising and acidic materials.
Store away from foodstuffs.
· Further information about storage conditions:
Store in cool, dry conditions in well sealed receptacles.
Protect from heat and direct sunlight.
Protect from humidity and water.

· Specific end use(s): No further relevant information available.

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:
UN 2413
Shipping information
Proper shipping name and description:
2413 TETRAPROPYL ORTHOTITANATE
Labels:
3
Special provisions / remarks
Remarks:
· Excepted quantities (EQ): E1
· Limited quantities (LQ): 5L
· Excepted quantities (EQ) Code: E1
Maximum net quantity per inner packaging: 30 ml
Maximum net quantity per outer packaging: 1000 ml
· Transport category: 3
· Tunnel restriction code: D/E
Shippingopen allclose all
Remarksopen allclose all

Marine transport (UN RTDG/IMDG)

UN number:
UN 2413
Shipping information
Proper shipping name and description:
TETRAPROPYL ORTHOTITANATE
Labels:
3
Special provisions / remarks
Remarks:
· Limited quantities (LQ): 5L
· Excepted quantities (EQ) Code: E1
Maximum net quantity per inner packaging: 30 ml
Maximum net quantity per outer packaging: 1000 ml

Air transport (UN RTDG/ICAO/IATA)

UN number:
UN 2413
Shipping information
Proper shipping name and description:
TETRAPROPYL ORTHOTITANATE
Labels:
3
Special provisions / remarks
Remarks:
UN No. 2413
Special provisions: -
Danger Code: 3L
UN packing group: III
PASSENGER AND CARGO AIRCRAFT:
Excepted Quantities: E1
Packing instruction: 355
max. net quantity per package: 60 L
Limited Quantity:
Packing instruction: Y344
max. net quantity per package: 10 L
CARGO AIRCRAFT:
Packing instruction: 366
max. net quantity per package: 220 L
GRACE recommends CARGO AIRCRAFT only.

Additional transport information

Additional information
Special provisions / remarks / other:
· Environmental hazards: Not applicable.
· Special precautions for user Warning: Flammable liquids.
· Danger code (Kemler): 30
· EMS Number: F-E,S-D
· Stowage Category: A
· Transport in bulk according to Annex II of Marpol and the IBC Code: Not applicable.

Exposure controls / personal protection

· Ingredients with limit values that require monitoring at the workplace:
67-63-0 propan-2-ol

WEL (Great Britain) Short-term value: 1250 mg/m³, 500 ppm
Long-term value: 999 mg/m³, 400 ppm

· DNELs (67-63-0 propan-2-ol)
Oral DNEL(long-systemic): 26 mg/kg bw /day (General population), ECHA 2011
Dermal DNEL(long-systemic): 89 mg/kg bw /day (General population), ECHA 2011; 888 mg/kg bw /day (Worker), ECHA 2011
Inhalative DNEL(long-systemic): 319 mg/m³ (General population), ECHA 2011; 500 mg/m³ (Worker), ECHA 2011

· PNECs (67-63-0 propan-2-ol)
PNEC 160 mg/kg (O), ECHA 2011
28 mg/kg (soil), ECHA 2011
552 mg/kg (sediment (freshwater)), ECHA 2011
552 mg/kg (sediment (marine water)), ECHA 2011
PNEC 140.9 mg/l (aqua-freshwater), ECHA 2011
140.9 mg/l (aqua-intermittent releases), ECHA 2011
140.9 mg/l (aqua-marine water), ECHA 2011
2,251 mg/l (Sewage Treatment Plant), ECHA 2011
· Additional information: Valid lists at time of creation were used as basis.

· Exposure controls
· Personal protective equipment:
· General protective and hygienic measures:
Keep away from foodstuffs, beverages and feed.
Immediately remove all soiled and contaminated clothing.
Wash hands before breaks and at the end of work.
Avoid contact with the eyes.
Avoid contact with the eyes and skin.
· Respiratory protection:
In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use self-contained respiratory protective device.
Filter A/P2
· Protection of hands:
Protective gloves.
Check the condition of the gloves prior to each use.
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation.
Preventive skin protection by use of skin-protecting agents is recommended.
· Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance of the glove material can not be calculated in advance and has therefore to be checked prior to the application.
Butyl rubber, BR
Nitrile rubber, NBR
Recommended thickness of the material: >= 0.7 mm
· Penetration time of glove material
EN 420: Minimum requirements for efficiency level 1 for all groups.
The exact break through time has to be obtained from the manufacturer of the protective gloves and has to be observed.
For the mixture of chemicals mentioned below the penetration time has to be at least 480 minutes (Permeation according to EN 374 Part 3: Level 6).
· For the permanent contact gloves made of the following materials are suitable:
Butyl rubber, BR
Nitrile rubber, NBR
· Not suitable are gloves made of the following materials:
Leather gloves
cloth gloves
· Eye protection:
Tightly sealed goggles
· Body protection: Protective work clothing.

Stability and reactivity

· Reactivity: No further relevant information available.
· Chemical stability: No decomposition if used according to specifications.
· Possibility of hazardous reactions: Violent reactions with strong alkalis and oxidising agents.
Conditions to avoid
In case of thermal decomposition caused by smouldering and incomplete combustion toxic fumes may be developed.
· Incompatible materials: Protect from contamination.
· Hazardous decomposition products:
Carbon monoxide and carbon dioxide
Metal oxide smoke

Disposal considerations

· Waste treatment methods
· Recommendation: Disposal must be made according to official regulations.
· Waste disposal key:
The disposal of the product has to be carried out in accordance with the legal requirements. EWC waste codes are strictly industry-oriented, therefore waste classification has to be done by the waste producer.
· Uncleaned packaging:
· Recommendation: Disposal must be made according to official regulations.