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EC number: 945-527-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- 1. SOFTWARE
OECD Toolbox Version 3.4
2. SMILES
Isomer 1, 5-Methacryloyloxy-1,3-dioxan : C=C(C)C(OC1COCOC1)=O
Isomer 2 4-Methacryloyloxymethyl-1,3-dioxolan : C=C(C)C(OCC1OCOC1)=O
Data source
Referenceopen allclose all
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
- Principles of method if other than guideline:
- - Software tool(s) used including version:
- Model used: OECD Toolbox 3.4 - GLP compliance:
- no
Test material
- Reference substance name:
- Reaction products of Glycerin formal and 2-Propenoic acid, 2-methyl-, methyl ester
- EC Number:
- 945-527-5
- Cas Number:
- 1620329-57-8
- Molecular formula:
- C8H12O4
- IUPAC Name:
- Reaction products of Glycerin formal and 2-Propenoic acid, 2-methyl-, methyl ester
Constituent 1
- Specific details on test material used for the study:
- SMILES
Isomer 1, 5-Methacryloyloxy-1,3-dioxan : C=C(C)C(OC1COCOC1)=O
Isomer 2 4-Methacryloyloxymethyl-1,3-dioxolan : C=C(C)C(OCC1OCOC1)=O
Results and discussion
Effect concentrationsopen allclose all
- Key result
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 265 mg/L
- Basis for effect:
- growth rate
- Remarks on result:
- other: QSAR
- Remarks:
- both isomers
- Key result
- Duration:
- 72 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 197 mg/L
- Basis for effect:
- growth rate
- Remarks on result:
- other: QSAR
- Remarks:
- both isomers
Any other information on results incl. tables
Toxicity (EC50, 72 h, growth rate) of the target chemical (265 mg/L) is predicted from category members using trend analysis based on 15 values within the range 2.28 - 836 mg/L from 15 category members. Category members are single
chemicals or mixtures and are selected based on the profile of the target chemical. Only chemicals having experimental data are listed in the category.
The target chemical FALLS within applicability domain of the prediction
The data used for calculating the current prediction is taken from 16 experimental values selected from the following database(s):
1. ECHA CHEM (studies on behalf of the registrant)
Toxicity (NOEC, 72 h, growth rate) of the target chemical (196 mg/L) is predicted from category members using trend analysis based on
14 values within the range 0.251 - 400 mg/L from 14 category members. Category members are single
chemicals or mixtures and are selected based on the profile of the target chemical. Only chemicals having
experimental data are listed in the category.
The target chemical FALLS within applicability domain of the prediction (see Section 4.3 for details).
The data used for calculating the current prediction is taken from 15 experimental values selected from
the following database(s):
1. ECHA CHEM (studies on behalf of the registrant)
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Remarks:
- The target chemical FALLS within applicability domain of the prediction
- Conclusions:
- EC50 Algae (72 h) growth rate of Glycerolformal methacrylate (both isomers) is 265 mg/l based mg/l on QSAR predicted from category members using trend analysis is predicted from category members using trend analysis based on
15 values within the range 2.28 - 836 mg/L from 15 category members. Category members are single chemicals or mixtures and are selected based on the profile of the target chemical. Only chemicals having experimental data are listed in the category.
NOEC Algae (72h) growth rate of Glycerolformal methacrylate (both isomers) is 197 mg/l based mg/l on QSAR predicted from category members using trend analysis is predicted from category members using trend analysis based on
15 values within the range 0.251 - 400 mg/L from 15 category members. Category members are single chemicals or mixtures and are selected based on the profile of the target chemical. Only chemicals having experimental data are listed in the category. - Executive summary:
EC50 Algae (72 h) growth rate of Glycerolformal methacrylate (both isomers) is 265 mg/l based mg/l on QSAR predicted from category members using trend analysis is predicted from category members using trend analysis based on
15 values within the range 2.28 - 836 mg/L from 15 category members. Category members are single chemicals or mixtures and are selected based on the profile of the target chemical. Only chemicals having experimental data are listed in the category.
NOEC Algae (72h) growth rate of Glycerolformal methacrylate (both isomers) is 197 mg/l based mg/l on QSAR predicted from category members using trend analysis is predicted from category members using trend analysis based on
15 values within the range 0.251 - 400 mg/L from 15 category members. Category members are single chemicals or mixtures and are selected based on the profile of the target chemical. Only chemicals having experimental data are listed in the category.
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