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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

The key ecotoxicity values for the registered substance SANDALWOOD AUSTROCALEDONIEN OIL are as follow:

-         Aquatic Invertebrates: 48-h EL50 was 1.96 mg test material/L (geo mean between three 48h-EL50)

-         Aquatic algae: 72-h ErL50 was 63.816 mg test material/L (experimental study)

Based on these results, the lowest acute E(L)C50 is higher than 1 mg/L.

Therefore, the substance would not be classified as acute 1 to aquatic organisms in accordance with the classification of the CLP.

Additional information

The registered substance is a Natural Complex Substance (UVCB) with a well-defined composition (typical % and ranges % of constituents).

Two experimental studies and one calculation were available to assess the acute toxicity of the registered substance on aquatic invertebrates. The experimental studies were performed under GLP conditions according to the OECD 202 guideline. They were performed in 48h closed semi-static tests using Water Accommodated Fractions (WAFs). On the other hand, an in-house calculation method was performed in order to imitate an OECD 202 study and guideline for Testing of Chemicals No. 23 (i.e. WAF conditions).

None of these three studies are regarded as key study, because they all present vulnerabilities. Indeed, it has been decided to use the results of these three studies in a weight of evidence approach and the key ecotoxicity value for that endpoint was the geometric mean between the three EL50.

Moreover, an experimental study was available to assess the toxicity of the registered substance on freshwater algae. The effect observed was the growth inhibition in a 72h static test, under GLP compliance according to the OECD 201 guideline using Water Accommodated Fractions (WAFs). The study presented some deviations but they were considered not to affect the integrity and the results. The validity criteria were respected and the study was considered acceptable for that endpoint.

Furthermore, short-term toxicity to fish was not provided in the dataset since the tonnage band (1 -10 tonnes/year) does not require that endpoint.

CLP Classification proposal

It is proposed to compare submission substance dataset to CLP environmental criteria laid down in CLP Regulation (including 2nd Adaptation to Technical Progress, Com Reg No 286/2011).

Acute aquatic hazard: not classified. Reasoning: lowest E(L)C50 higher than 1 mg/L.

Chronic aquatic hazard: category 2. Reasoning: adequate chronic toxicity data are not available, lowest acute E(L)C50 value is between 1 and 10 mg/L, not rapidly degradable substance with Log Kow of some constituents > 4