Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

The substance is predicted to have a LD50 of ca. 717 mg/kg bw.

Key value for chemical safety assessment

Acute toxicity: via oral route

Link to relevant study records
acute toxicity: oral
Type of information:
Adequacy of study:
other information
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
equivalent or similar to guideline
other: ECHA guidance on information requirements and chemical safety assessment Chapter R.6: QSARs and grouping of chemicals.
The applicability domain of predictions is assessed considering:

- Similar molecules with known experimental value.
- Accuracy of prediction for similar molecules.
- Concordance for similar molecules.
Key result
not specified
Dose descriptor:
Effect level:
ca. 717 mg/kg bw

The result appears reliable as the predicted compound is into the applicability domain of the model.

Interpretation of results:
Category 4 based on GHS criteria
The substance has a LD50 of ca. 717 mg/kg bw.
Endpoint conclusion
Dose descriptor:
717 mg/kg bw
Quality of whole database:
No experimental data are available. The database includes a QSAR prediction showing a good reliability. Overall, the quality of the whole database is limited.

Acute toxicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Acute toxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Justification for classification or non-classification

Overall, data are deemed to be inconclusive for classification.