Registration Dossier
Registration Dossier
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EC number: 285-749-3 | CAS number: 85136-25-0
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - Shake Flask Method)
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Principles of method if other than guideline:
- The substance contains as a main component x·sodium y·Lithium 3,3'-[(1-oxido-1,2-diazenediyl)bis[(2-methoxy-1,4-phenylene)-1,2-diazenediyl]]bis[4,5-dihydroxy-2,7-naphthalenedisulfonate]. Owing to this substance is ionisable, it was not possible to apply any of the OECD guidelines to study its partition coefficient n-octanol/water and, as is stated in the paragraph 107.4 of the OECD 107 Guideline, in these cases Pow can be calculated from individual solubilities in water and in octanol.
- GLP compliance:
- no
- Other quality assurance:
- other: ISO 9001-2008
- Type of method:
- estimation method (solubility ratio)
- Partition coefficient type:
- octanol-water
- Analytical method:
- other: weighed residues in n-octanol and water
- Key result
- Type:
- Pow
- Partition coefficient:
- 0.003
- Temp.:
- 23 °C
- pH:
- 6.83
- Key result
- Type:
- log Pow
- Partition coefficient:
- -2.49
- Temp.:
- 23 °C
- pH:
- 6.83
- Conclusions:
- The calculated log P o/w of the test substance is -2.49
Reference
Description of key information
The annex of guideline OECD 107 has been used as the basis of the calculation to determine the partition coefficient. The value of the partition coefficient has been estimated from the solubility of the test substance in the pure solvents.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -2.49
- at the temperature of:
- 23 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
