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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
26.02.2018 to 12.03.2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Version / remarks:
1995
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient - Shake Flask Method)
Version / remarks:
2008
GLP compliance:
yes (incl. QA statement)
Remarks:
consilab, Gesellschaft für Anlagensicherheit mbH, Industriepark Höchst, G830/G840, 65926 Frankfurt am Main (Germany)
Type of method:
flask method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Reference substance name:
L-Threonine, N-coco acyl derivs., monosodium salts
Cas Number:
90583-79-2
Molecular formula:
n/a
IUPAC Name:
L-Threonine, N-coco acyl derivs., monosodium salts
Test material form:
solid
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Ajinomoto Co., Inc., 15-1, Kyobashi 1-chome, Chuo-ku, Tokyo 104-8315, Japan, Batch No.: 160329
- Expiration date of the lot/batch: 2019-03-29
- Purity test date: 2016-06-09

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: stored at ambient temperature

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
-2.6
Temp.:
20 °C
Remarks on result:
other: pH value not specified

Applicant's summary and conclusion

Conclusions:
The log Pow of the test item was determined to be -2.6 at 20°C.
Executive summary:

The n-octanol/water partition coefficient log Pow was investigated in a study conducted according to OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method; 1995) and EU Method A.8 (Partition Coefficient - Shake Flask Method; 2008). Based on the results of preliminary tests, the log Pow was determined via the solubilities of the test item in the pure solvents using HPLC/UV/VIS as analytical method. The log Pow of the test item was determined to be -2.6 at 20°C.