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EC number: 292-282-9 | CAS number: 90583-79-2
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 26.02.2018 to 12.03.2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Version / remarks:
- 1995
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - Shake Flask Method)
- Version / remarks:
- 2008
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- consilab, Gesellschaft für Anlagensicherheit mbH, Industriepark Höchst, G830/G840, 65926 Frankfurt am Main (Germany)
- Type of method:
- flask method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- L-Threonine, N-coco acyl derivs., monosodium salts
- Cas Number:
- 90583-79-2
- Molecular formula:
- n/a
- IUPAC Name:
- L-Threonine, N-coco acyl derivs., monosodium salts
- Test material form:
- solid
Constituent 1
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Ajinomoto Co., Inc., 15-1, Kyobashi 1-chome, Chuo-ku, Tokyo 104-8315, Japan, Batch No.: 160329
- Expiration date of the lot/batch: 2019-03-29
- Purity test date: 2016-06-09
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: stored at ambient temperature
Study design
- Analytical method:
- high-performance liquid chromatography
Results and discussion
Partition coefficient
- Key result
- Type:
- log Pow
- Partition coefficient:
- -2.6
- Temp.:
- 20 °C
- Remarks on result:
- other: pH value not specified
Applicant's summary and conclusion
- Conclusions:
- The log Pow of the test item was determined to be -2.6 at 20°C.
- Executive summary:
The n-octanol/water partition coefficient log Pow was investigated in a study conducted according to OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method; 1995) and EU Method A.8 (Partition Coefficient - Shake Flask Method; 2008). Based on the results of preliminary tests, the log Pow was determined via the solubilities of the test item in the pure solvents using HPLC/UV/VIS as analytical method. The log Pow of the test item was determined to be -2.6 at 20°C.
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