2-hydroxypropyl [(1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl] carbonate

Surface tension

Link to relevant study record(s)

Reference

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

key study

Study period:

1994-03-14 to 1994-06-08

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Remarks:

The deviation from the guideline has no influence on the result of the study: since the water solubility of the test item is 88.8 mg/L no 90 % solution was used to determine the surface tension (54.1 mg/L = 61 %). Results were not corrected using the Harkins-Jordan correction table. Since the deviation from the guideline has no influence on the result of the study, this study is used as key study rated with RL2. The test item is considered to be surface active.

Qualifier:

according to guideline

Guideline:

OECD Guideline 115 (Surface Tension of Aqueous Solutions)

Version / remarks:

1981

Deviations:

yes

Remarks:

Please refer to the field "Rationale for reliability incl. deficiencies" above

Qualifier:

according to guideline

Guideline:

EU Method A.5 (Surface Tension)

Version / remarks:

1992

Deviations:

yes

Remarks:

Please refer to the field "Rationale for reliability incl. deficiencies" above

GLP compliance:

yes (incl. QA statement)

Remarks:

signed 1994-03-16

Type of method:

ring method

Key result

Surface tension:

50.2 mN/m

Temp.:

19 °C

Conc.:

54.1 mg/L

RESULTS

The peak heights relating to the standard and sample solutions are detailed below:

Solution	Mean peak height
Standard 567 mg/L	1.447 x 10^5
Standard 572 mg/L	1.465 x 10^5
Sample A	6.710 x 10^4
Sample B	7.133 x 10^4

Mean sample solution concentration = 5.41 x 10^-2 g/L

 

CALIBRATION

Reading [mN/m]	Temperature [°C]	Literature value [mN/m]	Calibration factor
72.4	19.0	72.90	1.007
72.5	19.0	72.90	1.006
72.5	19.0	72.90	1.006
72.4	19.0	72.90	1.007

Mean calibration factor = 1.007

 

SAMPLE SOLUTION

Time [min]	Reading [mN/m]	Temperature [°C]
83	49.9	19.0
103	49.9	19.0
117	49.9	19.0

Mean reading = 49.9 mN/m

Surface tension = reading x calibration factor =49.9 x 1.007 = 50.2 mN/m

Conclusions:

According to Council Directive 92/69/EEC A.5 and OECD Guideline 115 (1981), the surface tension of the aqueous solution at 19.0 °C ± 0.5 °C is σ = 50.2 mN/m. Since the surface tension is below 60 mN/m the test item has surface active properties.

Description of key information

The surface tension of the aqueous solution at 19.0 °C ± 0.5 °C is σ = 50.2 mN/m. Since the surface tension is below 60 mN/m the test item has surface active properties in accordance to Regulation (EC) No 440/2008.

Key value for chemical safety assessment

Surface tension:

50.2

in mN/m at 20°C and concentration in mg/L:

54.1