Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
basic toxicokinetics, other
Remarks:
Assessment
Type of information:
other: Assessment
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Expert judgement.
Justification for type of information:
There is no specific requirement to generate toxicokinetic information in the REACH Regulation (EC n.1907/2006). As reported in the Annex VIII, it is required to perform an assessment of the toxicokinetic behaviour of the substance to the extent that can be derived from the relevant available information.

Data source

Materials and methods

Principles of method if other than guideline:
Assessment.

Test material

Constituent 1
Reference substance name:
Reaction mass of dodecane-1-thiol and tridodecyl trithiophosphite
IUPAC Name:
Reaction mass of dodecane-1-thiol and tridodecyl trithiophosphite

Results and discussion

Preliminary studies:
General assessment.

Toxicokinetic / pharmacokinetic studies

Details on absorption:
General assessment.
Details on distribution in tissues:
General assessment.
Details on excretion:
General assessment.

Metabolite characterisation studies

Details on metabolites:
General assessment.

Bioaccessibility (or Bioavailability)

Bioaccessibility (or Bioavailability) testing results:
General assessment.

Applicant's summary and conclusion

Conclusions:
General assessment.
Executive summary:

General assessment.

Categories Display