Registration Dossier
Registration Dossier
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EC number: 263-760-4 | CAS number: 62924-31-6
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin irritation / corrosion
Link to relevant study records
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
- GLP compliance:
- yes (incl. QA statement)
- Species:
- rabbit
- Strain:
- New Zealand White
- Type of coverage:
- semiocclusive
- Vehicle:
- unchanged (no vehicle)
- Amount / concentration applied:
- dose of 0.5 g
- Duration of treatment / exposure:
- 4 hours
- Number of animals:
- 3
- Irritation parameter:
- erythema score
- Time point:
- 24/48/72 h
- Score:
- 0
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- No cutaneous reactions (erythema and oedema) were observed whatever the examination time (1,24,48,72 hours).
Reference
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
Justification for classification or non-classification
On the basis of the Registrant's experience, the substance causes skin and eye irritation.
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