6-tert-butyl-1,1-dimethylindan-4-yl methyl ketone

Particle size distribution (Granulometry)

Link to relevant study record(s)

Reference

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

11 November 2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

test procedure in accordance with generally accepted scientific standards and described in sufficient detail

Qualifier:

according to guideline

Guideline:

other: European Commission Guidance Document EUR 20268 ‘Determination of Particle Size Distribution, Fibre Length and Diameter Distribution of Chemical Substances’

Version / remarks:

(2002)

GLP compliance:

yes (incl. QA statement)

Type of method:

sieving

Size:

< 100 µm

Distribution:

6.41 %

Remarks on result:

other: Percentage of test item having an inhalable particle size of less than 100 µm.

Remarks:

Test item has been considered to be essentially non-inhalable.

Conclusions:

The percentage of test item having an inhalable particle size of less than 100 µm was determined to be 6.41%. The test item has been considered to be essentially non-inhalable (MMAD >100 µm).

Executive summary:

The percentage of test item having an inhalable particle size of less than 100 µm was determined to be 6.41% in a study performed under GLP using a procedure designed to be compatible with European Commission Guidance Document EUR 20268. The test item has been considered to be essentially non-inhalable (MMAD > 100 µm).

Description of key information

The percentage of test item having an inhalable particle size of less than 100 µm was determined to be 6.41%. The test item has been considered to be essentially non-inhalable (MMAD >100 µm).