Registration Dossier

Identification

Display Name:
Hydrocotyle asiatica, ext.
EC Number:
283-640-5
EC Name:
Hydrocotyle asiatica, ext.
CAS Number:
84696-21-9
Molecular formula:
not applicable
IUPAC Name:
Centella asiatica ext, Apiaceae, leaf, Ethanolic/Acqueous extraction

Type of substance

Composition:
UVCB
Origin:
other: natural vegetable origin

Total tonnage band

Total range:
10 - 100 tonnes per annum

REACH

Registered as:
FULL
Submitted:
Joint Submission

Publication dates

First published:
05-Apr-2018
Last modified:
15-Jun-2020

Chemical safety assessment

Performed for this substance:
YES

Compositions open all close all

Type:
boundary composition of the substance
State Form:
solid: bulk


Constituent 1
Chemical structure
Reference substance name:
O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl (2α,3β,4α)-2,3,23-trihydroxyurs-12-en-28-oate
EC Number:
240-851-7
EC Name:
O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl (2α,3β,4α)-2,3,23-trihydroxyurs-12-en-28-oate
CAS Number:
16830-15-2
Molecular formula:
C48H78O19
IUPAC Name:
[(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl](1S,2R,4aS,6aR,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate
Constituent 2
Chemical structure
Reference substance name:
O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl (2α,3β,4α,6β)-2,3,6,23-tetrahydroxyurs-12-en-28-oate
EC Number:
252-076-1
EC Name:
O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl (2α,3β,4α,6β)-2,3,6,23-tetrahydroxyurs-12-en-28-oate
CAS Number:
34540-22-2
Molecular formula:
C48H78O20
IUPAC Name:
[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-(3,4, 5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]oxymethyl]-3,4, 5-trihydroxyoxan-2-yl] 8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5, 6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate
Constituent 3
Chemical structure
Reference substance name:
(1S,2R,4aS,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
CAS Number:
464-92-6
Molecular formula:
C30H48O5
IUPAC Name:
(1S,2R,4aS,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
Constituent 4
Chemical structure
Reference substance name:
(1S,2R,4aS,6aR,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a, 7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
CAS Number:
18449-41-7
Molecular formula:
C30H48O6
IUPAC Name:
(1S,2R,4aS,6aR,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a, 7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
Constituent 5
Reference substance name:
Polyphenol
Molecular formula:
not applicable
IUPAC Name:
Polyphenol
Type:
legal entity composition of the substance
State Form:
solid: bulk


Constituent 1
Chemical structure
Reference substance name:
O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl (2α,3β,4α)-2,3,23-trihydroxyurs-12-en-28-oate
EC Number:
240-851-7
EC Name:
O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl (2α,3β,4α)-2,3,23-trihydroxyurs-12-en-28-oate
CAS Number:
16830-15-2
Molecular formula:
C48H78O19
IUPAC Name:
[(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl](1S,2R,4aS,6aR,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate
Constituent 2
Chemical structure
Reference substance name:
O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl (2α,3β,4α,6β)-2,3,6,23-tetrahydroxyurs-12-en-28-oate
EC Number:
252-076-1
EC Name:
O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl (2α,3β,4α,6β)-2,3,6,23-tetrahydroxyurs-12-en-28-oate
CAS Number:
34540-22-2
Molecular formula:
C48H78O20
IUPAC Name:
[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-(3,4, 5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]oxymethyl]-3,4, 5-trihydroxyoxan-2-yl] 8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5, 6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate
Constituent 3
Chemical structure
Reference substance name:
(1S,2R,4aS,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
CAS Number:
464-92-6
Molecular formula:
C30H48O5
IUPAC Name:
(1S,2R,4aS,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
Constituent 4
Chemical structure
Reference substance name:
(1S,2R,4aS,6aR,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a, 7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
CAS Number:
18449-41-7
Molecular formula:
C30H48O6
IUPAC Name:
(1S,2R,4aS,6aR,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a, 7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
Constituent 5
Reference substance name:
water and volatile substances
Molecular formula:
not applicable sum of watres and volatile substances
IUPAC Name:
water and volatile substances
Constituent 6
Reference substance name:
proteins natural
Molecular formula:
is not applicable
IUPAC Name:
proteins natural
Constituent 7
Reference substance name:
Aminoacid
Molecular formula:
not applicable
IUPAC Name:
Aminoacid
Constituent 8
Reference substance name:
Acids organic
Molecular formula:
not applicable
IUPAC Name:
Acids organic
Constituent 9
Reference substance name:
Polyphenol
Molecular formula:
not applicable
IUPAC Name:
Polyphenol
Constituent 10
Chemical structure
Reference substance name:
Tannins
EC Number:
215-753-2
EC Name:
Tannins
CAS Number:
1401-55-4
Molecular formula:
Not available
IUPAC Name:
1,3,6-tris-O-(3,4,5-trihydroxybenzoyl)hexopyranose
Constituent 11
Reference substance name:
Sugar free
Molecular formula:
not applicable
IUPAC Name:
Sugar free
Constituent 12
Reference substance name:
reducing sugar
Molecular formula:
not applicable
IUPAC Name:
reducing sugar
Constituent 13
Chemical structure
Reference substance name:
Flavonoids
Molecular formula:
not applicable
IUPAC Name:
Flavonoids
Constituent 14
Chemical structure
Reference substance name:
Sodium
EC Number:
231-132-9
EC Name:
Sodium
CAS Number:
7440-23-5
Molecular formula:
Na
IUPAC Name:
sodium
Constituent 15
Chemical structure
Reference substance name:
Potassium
EC Number:
231-119-8
EC Name:
Potassium
CAS Number:
7440-09-7
Molecular formula:
K
IUPAC Name:
potassium
Constituent 16
Chemical structure
Reference substance name:
Chlorine
EC Number:
231-959-5
EC Name:
Chlorine
CAS Number:
7782-50-5
Molecular formula:
Cl2
IUPAC Name:
chlorine

Registrants / Suppliers Details open all close all

Registrant / Supplier Registered Updated
Indena S.p.A. Viale Ortles,12 20139 Milan Italy 2018 2020

Administrative data open all close all

  • 01-2120762805-47-0000

Contact Persons responsible for the SDS