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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
9.8.2017-30.8.2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
comparable to guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
EU Method A.8 (Partition Coefficient - Shake Flask Method)
Deviations:
yes
Remarks:
Since the sample composition was complicated, it was not possible to determine all component concentrations by simple analytical methods. The concentrations were calculated by using gravimetric values of water and 2-octanol layers.
GLP compliance:
no
Other quality assurance:
ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
Type of method:
flask method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Reference substance name:
Active enzyme protein of β-Glucosidase (EC no. 232-589-7, CAS no. 9001-22-3, EC name: Glucosidase, β-, Enzyme Class no. 3.2.1.21)
Molecular formula:
Not available. See remarks.
IUPAC Name:
Active enzyme protein of β-Glucosidase (EC no. 232-589-7, CAS no. 9001-22-3, EC name: Glucosidase, β-, Enzyme Class no. 3.2.1.21)
Constituent 2
Reference substance name:
Proteins as constituents of enzyme deriving from the fermentation or extraction process
Molecular formula:
Not available. See remarks.
IUPAC Name:
Proteins as constituents of enzyme deriving from the fermentation or extraction process
Constituent 3
Reference substance name:
Carbohydrates as a constituent of enzyme deriving from the fermentation or extraction process
Molecular formula:
Not available. See remarks.
IUPAC Name:
Carbohydrates as a constituent of enzyme deriving from the fermentation or extraction process
Constituent 4
Reference substance name:
Lipids as a constituent of enzyme deriving from the fermentation or extraction process
Molecular formula:
Not available. See remarks.
IUPAC Name:
Lipids as a constituent of enzyme deriving from the fermentation or extraction process
Constituent 5
Reference substance name:
Inorganic salts as a constituent of enzyme deriving from the fermentation or extraction process
Molecular formula:
Not available. See remarks.
IUPAC Name:
Inorganic salts as a constituent of enzyme deriving from the fermentation or extraction process
Test material form:
liquid
Details on test material:
- Substance type: UVCB
- Physical state: liquid
- Lot/batch No.: ABK172131381
- Storage conditions: cool below 10 degrees of Celsius
Specific details on test material used for the study:
- Substance type: UVCB
- Physical state: liquid
- Lot/batch No.: ABK172131381

Study design

Analytical method:
other: Gravimetry.

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
0.02
Temp.:
21 °C
pH:
> 4 - <= 7

Applicant's summary and conclusion

Conclusions:
The partition constituent of water/2-octanol was determined by using the Shake Flash -method. Based on the results the Log Pow for the test item is 0.020.
Executive summary:

The partition constituent of water/2-octanol was determined by using the Shake Flash -method. Based on the results the Log Pow for the test item is 0.020.